POM-V Prescription Required

Ceffect 25 mg/ml Suspension for Injection for Cattle and Pigs

Active ingredient: Cefquinome

Form

Injection

Species

Cattle Pigs

Manufacturer

Emdoka

VMD MA No.

34534/4002

What it's used for

Cattle: Respiratory disease caused by Pasteurella multocida and Mannheimia haemolytica. Digital dermatitis, infectious bulbar necrosis and acute interdigit...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Cefquinome

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Ceffect 25 mg/ml Suspension for Injection for Cattle and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Cattle:
Respiratory disease caused by Pasteurella multocida and Mannheimia haemolytica.
Digital dermatitis, infectious bulbar necrosis and acute interdigital necrobacillosis (foul
in the foot).
Acute E.coli mastitis with signs of systemic involvement.
Calves:
E.coli septicaemia in calves.
Pigs:
For the treatment of bacterial infections of the lungs and respiratory tract caused by
Pasteurella multocida, Haemophilus parasuis, Actinobacillus pleuropneumoniae,
Streptococcus suis and other cefquinome-sensitive organisms.
Mastitis-Metritis-Agalactia syndrome (MMA) with involvement of E.coli,
Staphylococcus spp., Streptococcus spp. and other cefquinome sensitive organisms.
AN: 00605/2025 & 00606/2025
Piglets:
Reduction of mortality in cases of meningitis caused by Streptococcus suis.
For the treatment of:
Arthritis caused by spp., E. coli
organisms.
Epidermitis (mild or moderate lesions) caused by Staphylococcus hyicus.

1 mg cefquinome/kg
bw
(2 ml/50 kg bw)
Once daily for
3 or 5 consecutive days
Digital dermatitis,
infectious bulbar
necrosis and acute
interdigital
necrobacillosis (foul in
the foot)
Acute E. coli mastitis
with signs of systemic
involvement
1 mg cefquinome/kg
bw
(2 ml/50 kg bw)
Once daily for
2 consecutive days
CalvesE. coli septicaemia2 mg cefquinome/kg
bw
(4 ml/50 kg bw)
Once daily for
3 or 5 consecutive days
Pigs Respiratory disease2 mg cefquinome/kg
bw
(2 ml/25 kg bw)
Once daily for
3 consecutive days
MMA2 mg cefquinome/kg
bw
(2 ml/25 kg bw)
Once daily for
2 consecutive days.
PigletsMeningitis
Arthritis
Epidermitis
2 mg cefquinome/kg
bw
(2 ml/25 kg bw)
Once daily for
5 consecutive days
All treatments to be given by intramuscular injection. Studies have indicated the
advisability of giving second and subsequent injections at different injection sites.
The preferred injection site is in the muscular tissue of the mid-neck.
To ensure a correct dosage, body weight should be determined as accurately as
possible to avoid underdosing.
Before use shake the bottle for a minute or until the product appears adequately
resuspended.
The veterinary medicinal product does not contain an antimicrobial preservative.
Swab the septum before removing each dose. Use a dry sterile needle and syringe.
AN: 00605/2025 & 00606/2025
An appropriately graduated syringe must be used to allow accurate administration of
the required dose volume. This is particularly important when injecting small volumes,
for example when treating piglets. When treating groups of animals, use a draw-off
needle.
The rubber stopper of the 100 ml vial may be safely punctured up to 25 times and the
rubber stopper of the 250 ml vial may be safely punctured up to 50 times. The user
should choose the most appropriate vial size according to the target species and
body weight category of animals to be treated.

Do not use in case of hypersensitivity to β-lactam antibiotics, or to any of the
excipients.
Do not administer to animals less than 1.25 kg body weight.
Do not use in poultry (including eggs) due to risk of spread of antimicrobial resistance
to humans.

Cattle, pigs
Rare
(1 to 10 animals / 10 000
animals treated):
Hypersensitivity reaction.Undetermined frequency
(cannot be estimated from the
available data)
Injection site reaction
1
Tissue lesions are repaired 15 days after the last administration of the veterinary
medicinal product.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.

Special precautions for safe use in the target species:
In case of occurrence of allergic reaction, the treatment should be withdrawn.
The use of cefquinome should be restricted to appropriate use according to the
labelled indications in the target animal species.
Inappropriate use of the product may increase the prevalence of bacteria resistant to
cefquinome and may decrease the effectiveness of treatment with other beta lactam
antibiotics, due to the potential for cross resistance.
The product selects for resistant strains such as bacteria carrying extended spectrum
betalactamases (ESBL) and may constitute a risk to human health if these strains
disseminate to humans e.g. via food. For this reason, the product should be reserved
for the treatment of clinical conditions which have responded poorly, or are expected
to respond poorly (refers to very acute cases when treatment must be initiated
without bacteriological diagnosis) to first line treatment.
Official, national and regional antimicrobial policies should be taken into account
when the product is used. Increased use, including use of the product deviating from
the instructions given in the SPC, may increase the prevalence of such resistance.
Whenever possible, the product should only be used based on susceptibility testing.
The product is intended for treatment of individual animals. Do not use for disease
prevention or as a part of herd health programs. Treatment of groups of animals
should be strictly restricted to ongoing disease outbreaks according to the approved
conditions of use.
AN: 00605/2025 & 00606/2025
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Cephalosporins may cause hypersensitivity (allergy) following injection, inhalation,
ingestion or skin contact. Hypersensitivity to penicillins may lead to cross sensitivity
to cephalosporins and vice versa. Allergic reactions to these substances may
occasionally be serious.
• Do not handle this product if you know you are sensitised, or if you have been
advised not to work with such preparations.
• Handle this product with great care to avoid exposure, taking all recommended
precautions.
• If you develop symptoms following exposure such as a skin rash, you should seek
medical advice and show the doctor this warning. Swelling of the face, lips or
eyes, or difficulty with breathing, are more serious symptoms and require urgent
medical attention.
• Care should be taken to avoid accidental injection and contact with the skin. Wash
hands after use.
Special precautions for the protection of the environment:
Not applicable.

Due to an undesirable pharmacodynamic interaction, do not use cefquinome
simultaneously with pharmaceuticals acting bacteriostatically.

This veterinary medicinal product does not require any special storage conditions.

Cattle: Meat and offal: 5 days
Milk: 24 hours
Pigs: Meat and offal: 3 days

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.