POM-V Prescription Required

Bovilis Nasalgen-C Nasal Spray, Lyophilisate and Solvent for Suspension for Cattle

Active ingredient: Bovine coronavirus

Form

Drops

Species

Cattle

Manufacturer

Intervet International B.V.

VMD MA No.

EU/2/23/294/000

What it's used for

Onset of immunity: 5 days. Duration of immunity: 12 weeks.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Bovine coronavirus

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Bovilis Nasalgen-C Nasal Spray, Lyophilisate and Solvent for Suspension for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Onset of immunity: 5 days.
Duration of immunity: 12 weeks.

Administer a single dose of 2 ml reconstituted vaccine to the calf from the day of birth
onwards in one nostril.
Reconstitute the lyophilisate with the solvent (Unisolve) supplied as described below.
Ensure that the lyophilisate is completely reconstituted before use.
The reconstituted product is a colourless or off-yellow suspension.
Instructions for reconstitution:
For proper reconstitution of the lyophilisate, transfer the solvent to the vial with the
lyophilisate using a transfer needle or using a needle and syringe.
The 10-, 20-, and 50-dose presentations require a two-step reconstitution of the
solvent to the vial with the lyophilisate and back to the solvent vial.
See the table below for the appropriate volumes. The vacuum in the vaccine vial will
allow quick insertion of the solvent into the lyophilisate vial. Ensure complete
resuspension by shaking the vial. The vaccine suspension can be drawn up in a
syringe with a clean tip. Alternatively, the vial with reconstituted vaccine can be put in
a multi-dose applicator.
The vaccine is now ready for administration into the nostril, directly from the tip of the
syringe or applicator. A spraying device is not required.
When vaccinating animals, it is recommended to change syringes or tips of a multi-
dose applicator between animals to avoid transmission of pathogens.
Doses per vialSolvent volume required Dose volume 12 ml2 ml510 ml2 ml1020 ml2 ml2040 ml2 ml50100 ml2 ml

None.

Cattle:
Very common
(>1 animal / 10 animals treated):
Nasal discharge, Increased respiratory
rate, Cough
Elevated temperature
Common
(1 to 10 animals / 100 animals treated):
Ocular discharge
Elevated temperature up to 40.7 °C which normally resolves within three days.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

Vaccinate healthy animals only.
Animals should preferably be vaccinated at least 5–7 days before a period of stress
or increased infection pressure.

Special precautions for safe use in the target species:
Vaccinated cattle may excrete the vaccine strain nasally or orally following
vaccination. Excretion has been observed for up to 9 days following vaccination but
may persist longer. The vaccine strain can spread to other cattle. Spread to other
species has not been investigated and cannot be excluded.
It is recommended to vaccinate all calves of the herd.
Appropriate biosecurity procedures to limit the risk of introduction and spread of
bovine coronavirus infection in premises should be part of management tools.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Not applicable.
Special precautions for the protection of the environment:
Not applicable.

Safety and efficacy data are available which demonstrate that this vaccine can be
administered on the same day but not mixed with Bovilis INtranasal RSP Live. The
vaccines should be given into different nostrils. The product information of that
veterinary medicinal product should be consulted before administration.
No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product except the product mentioned above. A
decision to use this vaccine before or after any other veterinary medicinal product
therefore needs to be made on a case by case basis.

Lyophilisate:
Store in a refrigerator (2 C – 8 C).
Do not freeze.
Protect from light.
Solvent:
Store below 25 C if stored independently from the lyophilisate.
Do not freeze.
Reconstituted vaccine:
Store at room temperature.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.