POM-V Prescription Required

Bovilis INtranasal RSP Live, Nasal Spray, Lyophilisate and Solvent for Suspension for Cattle

Active ingredients: Bovine parainfluenza virus 3, Bovine respiratory syncytial virus

Form

Spray

Species

Cattle

Manufacturer

Intervet International B.V.

VMD MA No.

06376/3025

What it's used for

Onset of immunity: BRSV: 6 days (for calves vaccinated from the day of birth onwards); 5 days (for calves vaccinated from the age of 1 week onwards); PI3:...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Clinical information

Bovilis INtranasal RSP Live, Nasal Spray, Lyophilisate and Solvent for Suspension for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Onset of immunity: BRSV: 6 days (for calves vaccinated from the day of birth
onwards);
5 days (for calves vaccinated from the age of 1 week
onwards);
PI3: 1 week.
Duration of immunity: 12 weeks.

Calves can be vaccinated from the day of birth onwards.
Reconstitute lyophilisate with solvent as described below. Ensure that the lyophilisate is
completely reconstituted before use. The reconstituted vaccine is an orange/brown to
off-pink or pink coloured suspension.
Administer a single dose of 2 ml reconstituted vaccine per animal in one nostril.
Instructions for reconstitution:
1 and 5 dose presentations
For proper reconstitution of the lyophilisate, transfer the solvent to the vial with the
lyophilisate (2 ml for the 1 dose, 10 ml for the 5 dose; also see the table below) using a
needle and syringe. The vacuum in the vaccine vial will allow quick emptying of the
syringe. Then resuspend by shaking. The vaccine suspension can be drawn up in a
syringe with a clean tip. The vaccine in the syringe is now ready for administration,
directly from the tip of the syringe. A spraying device is not required.
10 and 20 dose presentations
For proper reconstitution of the lyophilisate, transfer 10 ml of the solvent to the vial with
the lyophilisate using a needle and syringe. The vacuum in the vaccine vial will allow
quick emptying of the syringe. Then resuspend by shaking. Completely draw up the
vaccine suspension and transfer it back to the solvent vial in order to get the correct
dose/volume ratio for the respective presentation (20 ml for the 10 dose, 40 ml for the
20 dose; also see the table below). The vaccine suspension can be drawn up in a
syringe with a clean tip. The vaccine in the syringe is now ready for administration,
directly from the tip of the syringe. A spraying device is not required.
When vaccinating animals, it is recommended to change syringes or tips of a multi-dose
syringe between animals to avoid transmission of pathogens.

None.

Cattle:
Very common
(>1 animal / 10 animals treated):
Nasal discharge
.
Elevated temperature
.
Common
(1 to 10 animals / 100 animals
treated):
Cough
, increased respiratory rate
.
Ocular discharge
.
Mild and transient. Occurs during two days following vaccination.
Minor and transient (very rarely up to 41.1 °C); normally resolves within four days.
Mild and transient. Normally resolves in three days.
Transient. Normally resolves within four days.
Mild and transient. Normally resolves in two days.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

Vaccinate healthy animals only.
Animals should be preferably vaccinated at least 5 – 7 days before a period of stress or
increased infection pressure.
The efficacy against BRSV may be reduced by presence of maternally derived
antibodies.

Special precautions for safe use in the target species:
Vaccinated calves may excrete the vaccine strains up to 12 days following vaccination.
It is recommended to vaccinate all calves of the herd.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Not applicable.
Special precautions for the protection of the environment:
Not applicable.

Safety and efficacy data are available which demonstrate that this vaccine can be
administered on the same day but not mixed with Bovilis Nasalgen-C. The vaccines
should be given into different nostrils. The product information of that veterinary
medicinal product should be consulted before administration.
No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product except the product mentioned above.
A decision to use this vaccine before or after any other veterinary medicinal product
therefore needs to be made on a case by case basis.

Lyophilisate:
Store in a refrigerator (2 C – 8 C).
Do not freeze. Protect from light.
Solvent:
Store below 25 °C if stored independently from the lyophilisate.
Do not freeze.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.