POM-V Prescription Required

Bovilis Cryptium Emulsion for Injection for Cattle

Active ingredient: Cryptosporidium parvum

Form

Injection

Species

Cattle

Manufacturer

MSD Animal Health UK Limited

VMD MA No.

01708/5089

What it's used for

Newborn calves: Onset of immunity: Passive immunity commences from the start of colostrum feeding. Duration of immunity: In calves that receive colostrum a...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Cryptosporidium parvum

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Bovilis Cryptium Emulsion for Injection for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Newborn calves:
Onset of immunity: Passive immunity commences from the start of colostrum feeding.
Duration of immunity: In calves that receive colostrum and transition milk as indicated and
which were challenged at birth, passive immunity has been demonstrated until 2 weeks of
age.

Administer the vaccine in the side of the neck.
Allow the vaccine to reach room temperature before use.
Shake well before and occasionally during use to ensure homogeneity of the vaccine prior
to administration.
Common aseptic procedures should be used during vaccination.
Only sterile syringes and needles should be used.
Use of a multidose applicator is recommended when vaccinating multiple animals.
One dose: 2 ml.
Primary vaccination consists of 2 doses, 4 to 5 weeks apart, in the third trimester of
pregnancy. To be completed at least 3 weeks before calving. These doses are preferably
administered at different sides of the animal.
Revaccination consists of 1 dose in the third trimester of each next pregnancy. To be
completed at least 3 weeks before calving.

None.

Cattle (pregnant heifers and cows):
Very common
(>1 animal / 10 animals treated):
Injection site swelling
, injection site pain,
injection site warmth, injection site
granuloma.
Elevated temperature
.
Uncommon
(1 to 10 animals / 1,000 animals treated):
Muscle inflammation
.
Injection site abscess
.
Mean size up to 14 cm, maximum size up to 40 cm, swellings reduce in size over time,
but may persist as chronic granulomatous inflammation extending from the injection site
for at least 125 days.
Mean increase up to 1 °C with a maximum of 1.8 °C, returning to normal on ultimately the
nd
day after vaccination.
Granulomatous haemorrhagic inflammatory reaction in dermal and subdermal tissues
with inflammation extending into the underlying muscular tissue.
An abscess up to 1 cm in diameter detected in the neck after the 3
rd
vaccination.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

Vaccinate healthy animals only.
Feeding of calves
The protection of calves depends on adequate ingestion of colostrum and transition milk
from vaccinated cows. It is recommended that all calves are fed colostrum and subsequent
transition milk during the first 5 days of life. At least 3 litres of colostrum should be fed
within the first 6 hours after birth.
To achieve optimum results a whole herd vaccination policy should be adopted.
Farm management should aim at reduction of exposure to C. parvum.

Special precautions for safe use in the target species:
Administration in the ischiorectal fossa has resulted in local painful chronic granulomatous
reactions up to 15 cm in diameter and in abscess formation (multiple small abscesses up
to 1 cm in diameter at postmortem 15 weeks after the first vaccination and 11 weeks after
second vaccination) in one out of two necropsied cows (the study included 9 cows).
Administration in the dewlap can give rise to extensive chronic inflammatory reactions up
to 30 cm in diameter which can lead to painful local reactions with possible persistent
impact on cow welfare.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
To the user:
This veterinary medicinal product contains mineral oil. Accidental injection/self-injection
may result in severe pain and swelling, particularly if injected into a joint or finger, and in
rare cases could result in the loss of the affected finger if prompt medical attention is not
given. If you are accidentally injected with this veterinary medicinal product, seek prompt
medical advice even if only a very small amount is injected and take the package leaflet
with you. If pain persists for more than 12 hours after medical examination, seek medical
advice again.
To the physician:
This veterinary medicinal product contains mineral oil. Even if small amounts have been
injected, accidental injection with this product can cause intense swelling, which may, for
example, result in ischaemic necrosis and even the loss of a digit. Expert, PROMPT,
surgical attention is required and may necessitate early incision and irrigation of the
injected area, especially where there is involvement of finger pulp or tendon.
Special precautions for the protection of the environment:
Not applicable.
Other precautions:
Not applicable.

Safety and efficacy data are available which demonstrate that this vaccine can be
administered on the same day but not mixed with Bovilis Rotavec Corona. The vaccines
should be given at different sites.
The product literature of Bovilis Rotavec Corona should be consulted before
administration. Different routes of administration should be respected.
No information is available on the safety and efficacy of this vaccine when used with any
other veterinary medicinal product except the product mentioned above. A decision to use
this vaccine before or after any other veterinary medicinal product therefore needs to be
made on a case-by-case basis.

Store in a refrigerator (2 C – 8 C).
Do not freeze.
Protect from light.
After broaching and first use, store upright and refrigerated (2 °C – 8 °C) until the next use.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.