POM-V Prescription Required

Bovilis Bovivac S Suspension for Injection for Cattle

Active ingredients: Salmonella dublin, Salmonella typhimurium

Form

Injection

Species

Cattle

Manufacturer

Intervet International B.V.

VMD MA No.

06376/3018

What it's used for

This product may also contribute to reducing S. typhimurium contamination of the environment. Specific experimental data to quantify the duration of immuni...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Salmonella dublin + Salmonel...

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Bovilis Bovivac S Suspension for Injection for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

This product may also contribute to reducing S. typhimurium contamination of the
environment.
Specific experimental data to quantify the duration of immunity, the effectiveness of a
single dose re- vaccination or the degree of protection from colostral antibodies has not
been generated.
Significant levels of immunity cannot be expected until two weeks after the second
dose of the primary vaccination course.

The use of automatic vaccination equipment is recommended.
The vaccine may be administered using a sterile needle and syringe, providing a fresh
sterile needle is used each time the rubber cap is punctured, to avoid contamination of
the remaining contents.
Primary vaccination course
Where diagnosis of salmonellosis caused by has been
confirmed, all at risk adult cattle, including lactating cows, dry cows, heifers, barren cows
and in-contact bulls (but excluding any with overt clinical signs of salmonellosis), should
receive two 5 ml injections separated by an interval of 21 days.
For pregnant cows, this primary vaccination course can be given irrespective of the
reproductive status. Any pregnant cows that have not calved within 8 weeks of the second
dose of vaccine should receive a further 5 ml dose of this product 3-4 weeks pre-calving.
Healthy calves from approximately 3 weeks of age may also be given a primary
vaccination course.
Calves should be given two 2 ml injections separated by an interval of 14 to 21 days.
Re-vaccination scheme
All cattle vaccinated with the primary vaccination course of this product should
receive a 5 ml injection at least two weeks prior to each period of risk or at intervals of
not more than 12 months thereafter.
As part of an overall herd management programme, for pregnant cattle, it is advised that
for each subsequent pregnancy, in order to maintain a sufficient level of active
immunisation to reduce S. dublin and S. typhimurium infections under field conditions, a
single injection of 5 ml should be administered approximately 3-4 weeks before calving.
The efficacy of this product has been established in the field using the recommended
programme of use. No specific experimental data are available in support of the
effectiveness of a single dose re- vaccination.
The use of automatic vaccination equipment is recommended. Use a vaccinator with
vented draw-off spike or similar device only.

None.

Cattle:
Very common
(>1 animal / 10 animals treated):
Injection site swelling
.
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Hypersensitivity reaction.
Typically, the swellings may be warm when compared with the surrounding area for up
to 5 days after vaccination. Maximum size is reached within 1-6 days after vaccination.
Complete resolution or reduction to clinically insignificant reactions within 2-3 weeks after
vaccination. Swellings may be painful on palpation for 1-2 days after vaccination, which
will not require veterinary intervention.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

Vaccinate healthy animals only.

Special precautions for safe use in the target species:
All stock showing overt clinical signs of salmonellosis at the time of the initial vaccination
programme should receive appropriate treatment and be fully vaccinated once they have
recovered. Any unvaccinated stock must be managed separately to vaccinated stock, with
no contact between the groups. Hygiene precautions must be instituted, where possible,
to prevent transfer of infection from one group to another.
All animals of a herd should be vaccinated.
The effect of maternally derived antibodies has not been studied, but it is likely that
high levels of maternally derived antibodies may interfere with the development of
active immunity in calves.
When vaccinating animals, stress should be avoided, particularly during pregnancy.
A small number of individuals may fail to respond to vaccination as a result of
immunological incompetence or for some other reason. In the face of an outbreak of
disease, it is therefore important to avoid vaccination of animals which have overt clinical
salmonellosis or intercurrent disease or which have a poor nutritional status. Such
animals must be isolated and treated as appropriate and then vaccinated upon clinical
recovery.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Not applicable.
Special precautions for the protection of the environment:
Not applicable.

No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product. It is therefore recommended that no other
vaccines should be administered within 14 days before or after vaccination with this
product.
A decision to use this vaccine before or after any other veterinary medicinal product
therefore needs to be made on a case by case basis.

Store in a refrigerator (2 ℃– 8 ℃). Do not freeze. Protect from light.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.