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Avishield IB GI-13, Lyophilisate for Oculonasal Suspension/Use in Drinking Water for Chickens

Active ingredient: Infectious bronchitis virus

Form

Lyophilisate

Species

Chickens

Manufacturer

Genera d.d.

VMD MA No.

43676/4005

What it's used for

For the active immunisation of chickens in order to reduce the detrimental effect on the ciliary activity resulting from infection by avian infectious bron...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Clinical information

Avishield IB GI-13, Lyophilisate for Oculonasal Suspension/Use in Drinking Water for Chickens — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

For the active immunisation of chickens in order to reduce the detrimental effect on
the ciliary activity resulting from infection by avian infectious bronchitis virus, serotype
793B (GI-13 lineage), which may be manifested in respiratory clinical signs.
Onset of immunity: 10 days after vaccination.
Duration of immunity: 56 days after vaccination.
Coarse spray or oculonasal use: from one day of age.
In drinking water use: from 7 days of age.

Revised: April 2022
AN: 01404/2021 & 01405/2022
Administer one dose per animal by either coarse spray, oculonasal or in drinking
water use. Where the number of chickens is between the standard dosages, the next
higher dosage should be used.
1. Coarse spray
It is recommended to resuspend 1000 doses of the vaccine in 150 - 300 ml of
distilled water. The number of doses to be used corresponds to the number of birds
in the flock.
The volume of water for reconstitution should be sufficient to ensure an even
distribution when sprayed onto the birds, and will vary according to the age of the
birds being vaccinated and the management system, however at least 150 – 300 ml
of water per 1000 doses is suggested
The reconstituted vaccine suspension should be spread evenly over the correct
number of chickens, at a distance of 30 – 40 cm using a coarse spray (targeted
average droplet size of 150 - 170 microns), preferably when the chickens are sitting
together in dim light. The spray apparatus should be free from sediments, corrosion
and traces of disinfectants and ideally should be used for vaccination purposes only.
During and after vaccination ventilation should be switched off in order to avoid
turbulences.
2. In drinking water use
Suspend the vaccine in cool and clean water without traces of chlorine, other
disinfectants or impurities in a number of doses corresponding to the number of birds
to be vaccinated.
Vaccine should be suspended immediately before use.
The volume of water for reconstitution depends on the age of the birds, the breed,
the management practice and weather conditions. By adding approximately 2 grams
of skimmed milk powder or 20 ml of liquid skimmed milk per litre of water the virus
retains its activity longer.
In order to determine the quantity of water in which vaccine will be suspended for the
vaccination of chickens in a younger age category (until third week of life), the
following guideline applies:
- multiplying the number of birds in the thousands with the day of life (e.g. 1
thousand of chickens in the 7th day of life = 1 x 7 = 7 L)
It is important to resuspend the vaccine in the amount of water which will be drunk
within 1.5 - 2.5 hours (taking into account the different types of drinking systems for
poultry).
In order to make the birds thirsty, withdraw the supply of drinking water up to 2 hours
prior to vaccination (depending on the air temperature).
Always make sure that there is food available when vaccinating. Birds will not drink if
they have no food to eat. The drinking system should be clean, without traces of
chlorine, other disinfectants or impurities.
3. Oculonasal use
Suspend 1000 doses of the vaccine in 100 ml distilled water.
A dose of reconstituted vaccine is 0.1 ml, i.e. two drops, irrespective of poultry age,
weight and type. Instil one drop (0.05 ml) into the eye and one drop (0.05 ml) into the
nose opening. Ensure that the nasal drop is inhaled before releasing the bird.

Revised: April 2022
AN: 01404/2021 & 01405/2022
None.
Tracheal rales have been observed very commonly between 1 and 13 days after
oculonasal vaccination. If they occur, they resolve spontaneously and do not need
treatment.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
Vaccinate healthy animals only.
Maternally Derived Antibodies (MDA) can interfere with the development of active
immunity. Chickens can be vaccinated in the presence of MDA:immunity in chickens
with MDA will be developed 21 days after vaccination.

Revised: April 2022
AN: 01404/2021 & 01405/2022

Special precautions for use in animals
All birds in the flock should be vaccinated at the same time.
The vaccine strain is excreted from respiratory and intestinal tract. Appropriate
measures should be taken to prevent contact between vaccinated and non-
vaccinated animals. Measures should be taken to prevent spread to wild animals.
Housing should be cleaned and disinfected after each production cycle.
The vaccine strain can spread to susceptible, unvaccinated chickens for a minimum
of 28 days following vaccination. It is possible that the vaccine virus can be spread to
non-target susceptible species.
Avishield IB GI-13 is intended to protect chickens against respiratory signs of disease
caused by IBV variant 793B serotype (GI-13 lineage) strain only and should not be
used as a replacement for other IBV vaccines. Care should be taken to avoid the
introduction of the variant strain into an area where it is not present.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Care should be taken when reconstituting and administering the vaccine. Wash and
disinfect hands and equipment after administration of the vaccine. When spraying the
vaccine, personal protective equipment consisting of a mask with eye protection
should be worn by the operator and staff.
No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case by
case basis.
Store and transport refrigerated (2 ºC - 8 ºC).
Protect from light.
Do not freeze.
Zero days.
5. IMMUNOLOGICAL PROPERTIES
Pharmacotherapeutic group: Live viral vaccines for domestic fowl, avian infectious
bronchitis virus
ATC vet code: QI01AD07
To stimulate active immunity in chickens against 793B serotype of avian infectious
bronchitis virus (vaccinal strain V-173/11 belongs to 793B serotype/GI-13 lineage).

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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