POM-V Prescription Required

Avipro Thymovac Lyophilisate for Use in Drinking Water

Active ingredient: Chicken anaemia virus strain Cux-1

Form

Lyophilisate

Species

Chickens

Manufacturer

Elanco GmbH

VMD MA No.

52127/3006

What it's used for

For the active immunisation: Onset of immunity: 4 weeks after vaccination Duration of immunity: 43 weeks after vaccination demonstrated by challenge. For p...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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1

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2

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Prescription required

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Clinical information

Avipro Thymovac Lyophilisate for Use in Drinking Water — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For the active immunisation:
Onset of immunity: 4 weeks after vaccination
Duration of immunity: 43 weeks after vaccination demonstrated by challenge.
For passive protection conferred to the breeder progeny against clinical signs and
lesions of chicken anaemia. The protection of the breeder progeny is guaranteed for up
to 51 weeks after vaccination of the breeder, and chicks are protected at one day old
(as demonstrated by challenge).
AN: 01709/2025 and 01710/2025

One dose should be administered to each bird.
Dosage and use:
Drinking water application:
•
required. Do not split large vials to vaccinate more than 1 house or drinking
system, as this may lead to mixing errors.
•
etc. are thoroughly clean and free of any trace of disinfectants, detergents etc.
•
Low-fat skimmed milk powder (i.e. < 1 % fat) may be added to the water (2 – 4
grams per litre) or skimmed milk (20 – 40 ml per litre of water) to improve the water
quality and to increase the stability of the virus. This, however, has to be done at
least 10 minutes prior to reconstitution of the vaccine.
•
should be taken to empty the ampoule and its top completely by rinsing them in
water.
•
is applied. All tubing should be emptied of plain water, so that the drinkers contain
only vaccine water. If water is still present, drain lines before applying vaccine.
AN: 01709/2025 and 01710/2025
•
Birds drinking behaviour varies, it may be necessary to withhold water on some
sites prior to vaccination in order to ensure that all birds drink during the
vaccination period.
•
•
birds in up to 2 hours. Apply diluted vaccine to cold and fresh water at a rate of
1,000 doses of vaccine to 20 – 40 litres of water for 1,000 chickens. If in doubt,
measure water intake the day before administering vaccine.
– Administer the reconstituted vaccine to birds immediately.
– Make sure that birds do not have access to unmedicated water during
vaccination.
Carefully follow the instructions for correct administration in order that all birds receive
the correct dose. Insufficient vaccination may lead to reduced efficacy.

None

Chickens:
None known.
AN: 01709/2025 and 01710/2025
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

Vaccinate healthy animals only.

Special precautions for safe use in the target species:
Vaccination should be performed from 8 weeks of age onwards, but no later than 6
weeks before the onset of lay in order to ensure that protective immunity has developed
prior to the onset of lay.
The vaccine strain can spread to unvaccinated chickens, since vaccinated chickens
may excrete the vaccine strain via the faeces for at least 14 days following vaccination.
Since the virus may cause clinical symptoms in very young chicks, a transfer to
unprotected birds must be avoided. Special precautions should be taken to avoid
spreading of the vaccine strain to laying hens, birds approaching lay and young birds
below 3 weeks of age. The vaccine should not be used in multi-age sites.
Avoid stress before, during and after vaccination.
The vaccine virus can be found in different organs and tissues between day 7 and day
49 after vaccination.
To reduce infection pressure before onset of immunity, the litter should be removed, and
the poultry house should be cleaned between the raising passages.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
The vaccine contains live virus, therefore, personal protective equipment consisting of
gloves, glasses or goggles should be worn when handling the veterinary medicinal
product to avoid any contamination, e.g. by sprinkling or spilling.
Care should also be taken in handling poultry faeces as vaccine virus may be excreted
via the faeces for at least 14 days.
Wash and disinfect hands and equipment after use.
Special precautions for the protection of the environment:
Not applicable

No information is available on the safety and efficacy of this vaccine when used with any
other veterinary medicinal product. A decision to use this vaccine before or after any
other veterinary medicinal product therefore needs to be decided on a case-by-case
basis.

Store and transport refrigerated (2 °C – 8 °C). Protect from direct sunlight. Do not
freeze.
Protect the reconstituted vaccine from direct sunlight and temperatures of above 25 °C.
Do not freeze.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.