POM-V Prescription Required

Apravet 100 g/kg Premix for Medicated Feeding Stuff for Pigs

Active ingredient: Apramycin Sulfate

Form

Premix

Species

Pigs

Manufacturer

Huvepharma N.V.

VMD MA No.

30282/4019

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Apramycin Sulfate

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Apravet 100 g/kg Premix for Medicated Feeding Stuff for Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

The dosage is 4 000-8 000 IU apramycin/kg of bodyweight per day (equivalent to 4-8
g of the veterinary medicinal product per 100kg of bodyweight per day).
Administer as the sole feeding stuff for at least 21 days. It is recommended to mix the
required quantity of the veterinary medicinal product with a small amount of feed (20
– 50 kg) before mixing it in the total volume.
The intake of medicated feed depends on the clinical condition of the animals. In
order to obtain the correct dosing, the concentration of apramycin may need to be
adjusted accordingly.
To adjust dosing properly the following calculation can be used:
… g product/kg b.w./day x average b.w. of pigs (kg) = … g of the product/kg of feed
average daily intake of feed (kg/animal)
Medicated feed may be pelleted using a pre-conditioning step for 5 minutes at a
temperature not exceeding 85°C.
AN: 02749/2024 & 02750/2024

Do not use in the cases of hypersensitivity to the active substance, to other
aminoglycosides or to any of the excipients.
Do not use in animals suffering from kidney disorders.
Do not use in cats.
AN: 02749/2024 & 02750/2024

Pigs:
None known.
AN: 02749/2024 & 02750/2024
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

The uptake of medication by animals can be altered as a consequence of illness. In
case of insufficient uptake of feed animals should be treated parenterally.
The use of the veterinary medicinal product should be combined with good
management practices e.g. good hygiene, proper ventilation, no overstocking.

Special precautions for safe use in the target species:
Use of the veterinary medicinal product should be based on susceptibility testing of
the target pathogen(s). If this is not possible, therapy should be based on
epidemiological information and knowledge of susceptibility of the target pathogens
at farm level, or at local/regional level.
Use of the veterinary medicinal product should be in accordance with official, national
and regional antimicrobial policies.
Use of the veterinary medicinal product deviating from the instructions given in the
Summary of Product Characteristics may increase the prevalence of bacteria
resistant to the apramycin and may decrease the effectiveness of treatment with
aminoglycosides due to the potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
People with known hypersensitivity to apramycin should administer the veterinary
medicinal product with caution.
During preparation and administration of the medicated feedingstuff, skin, eye and
oral contact with the veterinary medicinal product, as well as inhalation of dust,
should be avoided. Personal protective equipment consisting of suit, gloves and an
appropriate dust mask (either a disposable half mask respirator conforming to
European Standard EN149 or a non-disposable respirator conforming to European
Standard EN140 with a filter to EN 143) should be worn when handling the veterinary
medicinal product.
Wash any contaminated skin. Wash hands carefully with soap and water after
handling of the veterinary medicinal product. In the event of accidental ingestion,
seek medical assistance immediately and show the package label.
Special precautions for the protection of the environment:
Not applicable.

In certain conditions with a high degree of humidity there might be an apparent
interaction with lectins.
Aminoglycosides may have a negative influence on the kidney function. The
administration of these agents to animals suffering from renal impairment or in
combination with agents that also affect renal function may therefore present a risk of
intoxication.
Do not administer with other aminoglycosides due to their nephrotoxic potential.
Aminoglycosides may cause neuromuscular blockade. It is therefore recommended
to take such an effect into account when anaesthetising treated animals.

Veterinary medicinal product as packaged for sale: Do not store above 25C. Store in
the original package. Store in a dry place.
Veterinary medicinal product after first opening of the immediate packaging: Do not
store above 25°C.
Medicated feed (mashed and pelleted): Do not store above 25°C.

Pigs:
Meat and offal: 1 day.
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This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.