Aivlosin 625 mg/g Granules for Use in Drinking Water for Pigs

Select the correct number of sachets according to the amount of product
required.

Issued: December 2024
AN: 02144/2023
The 40 g sachet is sufficient to treat a total of 5,000 kg of pigs (e.g. 250 pigs
with the heaviest pig weighing 20 kg) for one day.
The 160 g sachet is sufficient to treat a total of 20,000 kg of pigs (e.g. 400 pigs
with the heaviest pig weighing 50 kg) for one day.
The 400 g sachet is sufficient to treat a total of 50,000 kg of pigs (e.g. 1000 pigs
with the heaviest pig weighing 50 kg) for one day.
Swine enzootic pneumonia caused by susceptible strains of Mycoplasma
hyopneumoniae
The dose is 10 mg tylvalosin per kg bodyweight per day in drinking water for 5
consecutive days.
Calculate the total amount of product required with the following formula:
Total weight of product in grams = total bodyweight of the heaviest pig to be
treated in kg x number of pigs to be treated x 10 / 625.
Select the correct number of sachets according to the amount of product
required.
The 40 g sachet is sufficient to treat a total of 2,500 kg of pigs (e.g. 125 pigs
with the heaviest pig weighing 20 kg) for one day.
The 160 g sachet is sufficient to treat a total of 10,000 kg of pigs (e.g. 200 pigs
with the heaviest pig weighing 50 kg) for one day.
The 400 g sachet is sufficient to treat a total of 25,000 kg of pigs (e.g. 500 pigs
with the heaviest pig weighing 50 kg) for one day.
Mixing instructions:
In order to achieve a correct dose, accurate and properly calibrated equipment
should be used for weighing out the required amount of product.
The veterinary medicinal product may be mixed directly into the drinking water
system or first mixed as a stock solution into a smaller amount of water, which
is then added into the drinking water system.
When mixing the product directly into the drinking water system, the contents of
the sachet should be sprinkled onto the surface of the water and mixed
thoroughly until a clear solution is produced (usually within 3 minutes).
When preparing a stock solution, the maximum concentration should be 40 g of
product per 1,500 ml, 160 g of product per 6,000 ml or 400 g of product per
15,000 ml water and it is necessary to mix the solution for 10 minutes. After this
time, any remaining cloudiness will not affect the efficacy of the veterinary
medicinal product.

Issued: December 2024
AN: 02144/2023
Only a sufficient amount of medicated drinking water should be prepared to
cover the daily requirements.
Medicated drinking water should be replaced every 24 hours.
After end of the medication period, the water supply system should be cleaned
appropriately to avoid intake of subtherapeutic amounts of the active substance.
As an adjunct to medication, good management and hygiene practices should
be introduced in order to reduce the risk of infection and to control the build-up
of resistance.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
No signs of intolerance have been observed in pigs at up to 100 mg tylvalosin
per kg bodyweight per day for 5 days.
4.11 Withdrawal period(s)
Meat and offal: 2 days.
5.