Synulox is the most commonly prescribed veterinary antibiotic in the UK. It contains amoxicillin and clavulanic acid (the same combination as the human antibiotic Augmentin/Co-amoxiclav) and is used to treat a wide range of bacterial infections in dogs and cats.

Price Comparison

Synulox 250mg palatable tablets (10 tablets):

  • From your vet: £12–£25
  • Online pharmacies: £8–£16

Synulox 500mg palatable tablets (10 tablets):

  • From your vet: £18–£35
  • Online pharmacies: £12–£22

Generic Alternative: Clavaseptin

Clavaseptin is a generic version of Synulox containing the same active ingredients at the same strengths. It is bioequivalent and typically 15–25% cheaper. Ask your vet if they are willing to prescribe generic amoxicillin/clavulanic acid rather than branded Synulox.

Common Uses

  • Skin infections (pyoderma, hot spots, wound infections)
  • Urinary tract infections
  • Respiratory infections
  • Dental infections and post-dental surgery
  • Ear infections (alongside topical treatment)
  • Bite wounds and abscesses

Typical Course Length and Cost

Most infections require 5–14 days of treatment. A typical 7-day course for a medium-sized dog on Synulox 250mg (one tablet twice daily) costs:

  • At the vet: £18–£40 (including dispensing)
  • Online pharmacy: £10–£20 (plus prescription fee of £10–£25)

For short antibiotic courses, the prescription fee may negate the saving from buying online. Prescriptions are most worthwhile for long courses or repeat prescriptions for chronic conditions.

Responsible Antibiotic Use

Antibiotic resistance is a growing concern in both human and veterinary medicine. Always complete the full course prescribed by your vet, even if your pet seems better. Never use leftover antibiotics from a previous course without veterinary advice.

Last updated: March 2026. Sources: VetCost pharmacy price data, VMD product datasheet.