Simparica Trio is a monthly chewable tablet for dogs that provides triple protection: fleas, ticks, and worms (heartworm, roundworm, and hookworm). It contains sarolaner, moxidectin, and pyrantel. It competes directly with NexGard Spectra and is sometimes cheaper.
Price Comparison (3-Pack, Medium Dog 10-20kg)
- From your vet: £40–£60
- Online pharmacies: £28–£42
- Saving per 3-pack: £10–£20
Simparica Trio vs NexGard Spectra
Both products are monthly chewable tablets that combine flea/tick and wormer treatment. The key differences:
- Active ingredients: Simparica Trio uses sarolaner; NexGard Spectra uses afoxolaner. Both are isoxazoline-class flea/tick killers
- Speed of kill: Both kill fleas within hours and ticks within 8–12 hours
- Price: Simparica Trio is often 5–10% cheaper, though this varies by pharmacy
- Lungworm: NexGard Spectra does not cover lungworm; Simparica Trio's moxidectin does provide some lungworm protection
- Minimum age: Simparica Trio from 8 weeks; NexGard Spectra from 8 weeks
Who Makes It?
Simparica Trio is made by Zoetis, the world's largest animal health company. NexGard Spectra is made by Boehringer Ingelheim. Both are major, reputable pharmaceutical manufacturers.
How to Buy Cheaper
- Ask your vet for a written prescription specifying Simparica Trio
- Compare prices across online pharmacies — prices vary by 20–30% between pharmacies
- Buy 6-packs instead of 3-packs for a per-tablet discount
- Check VetCost's medication price comparison tool for current prices
Last updated: March 2026. Sources: VetCost pharmacy price data, VMD product datasheet.