Zitac Vet 200 mg Tablets for Dogs
Active ingredient: Cimetidine
Form
Tablet
Species
Manufacturer
Intervet International B.V.
VMD MA No.
06376/5045
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Paying less for Cimetidine
-
1
Ask your vet for a written prescription
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2
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The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.
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Prescription required
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Zitac Vet 200 mg Tablets for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
administered three times daily by the oral route (see indicative table below). The
concomitant use of appropriate dietary measures is strongly recommended. In
clinical trials the efficacy of cimetidine has only been studied concomitantly with a
hypoallergenic diet.
Table: Number of Zitac vet 200 mg tablets to be administered three times daily
according to body weight.
Weight (kg)Number of Zitac
vet 200 mg
tablets
11 to 20½21 to 40141 to 601 ½
Recommended treatment scheme: reduction of vomiting is achieved in about 2 weeks.
Animals should however be treated for at least 2 weeks after the remission of clinical
signs, so a minimum treatment duration of 28 days is usually necessary and therefore
recommended. If considered successful, medication should be withdrawn for 2 weeks.
If vomiting occurs again, treatment can be re-initiated without risk of intolerance.
Depending on the response, treatment can be adapted to the individual animal
until the response is considered to be adequate and continued. Dietary measures
should always be maintained.
Very common
(>1 animal / 10 animals treated):
Mammary gland swelling
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Prostate weight reduction
1
Transient and self-resolving, slight swelling (gynaecomastia); anti-androgenic
activity.
reversible, with no impact on reproductive performances
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian,
to either the marketing authorisation holder or the national competent authority via
the national reporting system. See the package leaflet for respective contact
details.
histopathological changes associated with gastritis. It is recommended that dogs
showing persistent vomiting should undergo appropriate investigations to
diagnose the underlying cause before starting treatment. This is especially
important in older animals. The reduction of gastric acidity caused by cimetidine
may contribute to bacterial overgrowth and antigenic stimulation.
Special precautions for safe use in the target species:
In case of renal dysfunction, adjustment of the dose may be required as the
clearance of cimetidine may be decreased. If the response to treatment is poor
within 15 days, the diagnosis and treatment plan should be re- evaluated.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals:
None.
Special precautions for the protection of the environment:
Not applicable.
elimination of some drugs can be reduced. Clinically relevant interactions may
occur with compounds having a narrow therapeutic index, e.g. beta-blockers,
calcium channel blockers, benzodiazepines, barbiturates, phenytoin, theophylline,
aminophylline, warfarin and lidocaine. Doses of such drugs may need to be
reduced when administered concomitantly with cimetidine.
Page 3 of 6The increased gastric pH resulting from cimetidine administration may lead to
reduced absorption of drugs requiring an acid medium for absorption. It is
recommended that at least 2 hours should elapse between administration of
cimetidine and aluminium or magnesium hydroxide, metoclopramide, digoxin or
ketoconazole when possible.
halves should be stored in the original blister pocket in order to protect from light.
4.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Cimetidine
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Alternative options to consider
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