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POM-VPS Prescription Required

Zerofen Worm Drench 2.5% w/v Oral Suspension for Sheep and Cattle

Active ingredient: Fenbendazole

Form

Liquid

Species

Cattle Sheep

Manufacturer

Chanelle Pharmaceuticals Manufacturing Ltd

VMD MA No.

08749/3029

What it's used for

Zerofen 2.5% is a broad spectrum anthelmintic for the control of mature and developing immature forms of the following major species of roundworm in sheep...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Fenbendazole

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Zerofen Worm Drench 2.5% w/v Oral Suspension for Sheep and Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Zerofen 2.5% is a broad spectrum anthelmintic for the control of mature and
developing immature forms of the following major species of roundworm in
sheep and cattle.
In sheep it is effective against benzimidazole susceptible strains of the following
parasites:
Gastro-intestinal roundworms: Ostertagia, Haemonchus, Trichostrongylus,
Nematodirus, Cooperia, Oesophagostomum, Chabertia, Bunostomum and
Strongyloides species.
Lungworms:
It is usually effective for the control of tapeworms, spp, in sheep.
Zerofen may be useful for the control of Trichuris in sheep.
In cattle it is effective against the following parasites:
Gastro-intestinal roundworms: Ostertagia, Cooperia, Trichostrongylus,
Nematodirus, Haemonchus, Oesophagostomum, Bunostomum, Strongyloides and
Trichuris species. Lungworms: Dictyocaulus viviparus.
It is usually effective against inhibited larvae of Ostertagia species in cattle.

Revised: September 2025
AN: 01687/2025
Zerofen 2.5% has an ovicidal effect on nematode eggs.
To ensure administration of a correct dose, body weight should be determined
as accurately as possible; accuracy of the dosing device should be checked.
Cattle:
bodyweight,
(3 ml per 10 kg bodyweight)
Sheep:
bodyweight,
(1 ml per 5 kg bodyweight)
Sheep over 75 kg should be given a further 2 ml for each additional 10 kg
bodyweight.
Do not mix with other products.
Not applicable
Intensive use or misuse of anthelmintics can give rise to resistance. To
reduce this risk dosing programmes should be discussed with your
veterinary advisor. Fenbendazole belongs to the Benzimidazole (1–BZ)
class of anthelmintics.

Revised: September 2025
AN: 01687/2025
Care should be taken to avoid the following practices because they increase the
risk of development of resistance and could ultimately result in ineffective
therapy:
•
an extended period of time.
•
misadministration of the product, or lack of calibration of the dosing device
(if any).
Suspected clinical cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test).
Where the results of the test(s) strongly suggest resistance to a particular
anthelmintic belonging to another pharmacological class and having a different
mode of action should be used.
Resistance to benzimidazoles has been reported in Teladorsagia, Haemonchus,
Cooper and Trichostrongylus species in small ruminants. Therefore, the use of
this product should be based on local (regional, farm) epidemiological
information about susceptibility of nematodes and recommendations on how to
limit further selection for resistance to anthelmintics.

Shake container before use.
i. Special precautions for use in animals
Intensive use or misuse of anthelmintics can give rise to resistance.
To reduce this risk dosing programmes should be discussed with
your veterinary advisor.
ii. Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Direct contact with skin should be kept to a minimum. Wear suitable
protective clothing including impermeable rubber gloves. Wash hands
after use.
interaction
None known
Animals must not be slaughtered for human consumption during treatment.
Sheep may be slaughtered for human consumption only after 21 days from
the last treatment. Cattle may be slaughtered for human consumption only
after 14 days from the last treatment.
Milk for human consumption must not be taken during treatment. Milk for
human consumption may be taken from cows only after 132 hours from the
last treatment.
Do not use in sheep producing milk for human consumption.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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