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POM-V Prescription Required

Vetmedin (Pimobendan)

Active ingredient: Pimobendan

Inodilator for treatment of canine congestive heart failure. Improves cardiac contractility and reduces cardiac workload.

Form

Chewable

Strength

1.25mg to 10mg

Species

Dog

What it's used for

For the treatment of dilated cardiomyopathy in the preclinical stage (asymptomatic with an increase in left ventricular end-systolic and end-diastolic diam...

Full indications, dosage and side effects ↓

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Pimobendan

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Vetmedin (Pimobendan) — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For the treatment of dilated cardiomyopathy in the preclinical stage (asymptomatic
with an increase in left ventricular end-systolic and end-diastolic diameter) in
Doberman Pinschers following echocardiographic diagnosis of cardiac disease.
Do not shake the bottle before or during use to avoid foaming.
To ensure a correct dosage, the bodyweight should be determined as accurately as
possible.
A dosage range of 0.2 mg to 0.6 mg pimobendan/kg bodyweight, divided into two
daily doses, should be respected. The preferrable daily dose is 0.5 mg
pimobendan/kg bodyweight divided into two daily doses given approximately
12 hours apart (i.e., 0.25 mg pimobendan/kg bodyweight equivalent to 0.17 ml of the
veterinary medicinal product twice daily).
The solution should be given using the measuring syringe provided in the package.
The syringe has a kg bodyweight scale with 0.5 kg increments up to a bodyweight of
12 kg and fits onto the bottle. Each 1 kg increment corresponds to 0.25 mg
pimonbendan. The total bodyweight of the animal should be used for each
administration. For example, for a 6 kg dog, the veterinary medicinal product should
be drawn up to the 6 kg mark on the syringe for each administration (this equates to
a 0.25 mg pimobendan/kg bodyweight dose per administration). Do not exceed the
recommended dosage.
Each dose should be given directly into the mouth on an empty stomach,
approximately one hour before feeding. After administration, close the bottle tightly
using the cap. Clean the outside of the syringe by wiping with a clean, dry cloth or
tissue after each use. The contaminated tissue should be immediately disposed of.
If the syringe clogs, rinse without removing the plunger by using water and wiping the
outside of the syringe dry with a clean cloth or tissue. To avoid contamination, use
the provided syringe only to administer this oral solution. The used syringe should be
stored with the veterinary medicinal product in the original carton.
Pimobendan may also be used in combination with a diuretic e.g., furosemide.
Advice on correct administration
The veterinary medicinal product consists of a bottle
sealed with a child-resistant cap A, a second child-resistant
cap with integrated plug-in adapter B and a measuring
dosing syringe with a kg-bodyweight scale C.
Do not shake the bottle prior to use (this avoids foaming).
Open the bottle in an upright position by pressing down on
the child-resistant cap A and simultaneously turning the
cap anticlockwise. Discard the white cap A.
Tightly close the bottle using the cap B and turn
simultaneously the cap clockwise. The cap B contains an
integrated plug-in adapter which should automatically
attach to the bottle A. Ensure the cap is tightly closed to
appropriately insert plug.
Remove the cap B from the bottle by pressing down on the
child-resistant cap and simultaneously turning the cap
anticlockwise and gently push the end of the dosing
syringe
Turn the bottle and syringe upside down.
Pull the plunger out and fill the dosing syringe to the dose
prescribed by your veterinarian.
Turn the bottle upright and remove the dosing syringe from
the bottle Close the bottle with cap B.
Put the end of the doing syringe C into your dog´s mouth
and push the plunger to give the prescribed dose.
Do not use pimobendan in hypertrophic cardiomyopathies or in diseases in which an
improvement in cardiac output cannot be achieved for functional or anatomical
reasons (e.g., aortic stenosis).
Do not use in cases of severe impairment of liver function, since pimobendan is
metabolised mainly via the liver.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Dogs:
Rare
(1 to 10 animals / 10 000
animals treated):
- Vomiting
, diarrhoea
- Anorexia
, lethargy
- Increased heart rate
1,3
- Increase in mitral valve regurgitation
Very rare
(< 1 animal / 10 000 animals
treated, including isolated
reports):
- Mucosa petechiae
, haemorrhage
(subcutaneous)
1
These effects are dose-dependent and can be avoided by reducing the dose.
Transient
Due to a slight positively chronotropic effect.
Observed during chronic pimobendan treatment in dogs with mitral valve
disease.
A relationship with pimobendan has not been clearly established, signs
disappear when the treatment is withdrawn.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
The veterinary medicinal product has not been tested in cases of asymptomatic DCM
in Dobermans with atrial fibrillation or sustained ventricular tachycardia.

Special precautions for safe use in the target species:
In dogs with existing diabetes mellitus, blood glucose should be tested regularly
during treatment with pimobendan.
For use in the preclinical stage of dilated cardiomyopathy (asymptomatic with an
increase in left ventricular end-systolic and end-diastolic diameter), a diagnosis
should be made by means of a comprehensive cardiac examination (incl.
echocardiographic examination and possibly Holter monitoring).
Monitoring of cardiac function and morphology is recommended in animals treated
with pimobendan.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
People with known hypersensitivity to pimobendan or any other excipients should
avoid contact with the veterinary medicinal product.
This veterinary medicinal product may cause skin and eye irritation. Avoid contact
with skin and eyes. In case of contact with the eyes or spillage onto the skin,
immediately rinse thoroughly with water. Wash hands after use.
Accidental ingestion, especially by a child, may lead to the occurrence of tachycardia,
orthostatic hypotension, flushing of the face and headaches.
To avoid accidental ingestion, do not leave a filled syringe unattended and store the
bottle and used syringe in the original carton in order to prevent children from getting
access to the veterinary medicinal product.
Close the bottle tightly with the cap directly after removal of the required amount of
solution.
The veterinary medicinal product must be used and kept out of sight and reach of
children.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.
In pharmacological studies no interaction between the cardiac glycoside ouabain
(strophanthin) and pimobendan was observed. The pimobendan-induced increase in
cardiac contractility is attenuated by the calcium antagonists verapamil and diltiazem
and by the β-antagonist propranolol.
Store below 30°C.
Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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Available Pack Sizes

50
100

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