Vetmedin 1.5 mg/ml Oral Solution for Dogs
Active ingredient: Pimobendan
Form
Liquid
Species
Manufacturer
Boehringer Ingelheim Animal Health UK Limited
VMD MA No.
08327/5028
What it's used for
For the treatment of canine congestive heart failure originating from dilated cardiomyopathy or valvular insufficiency (mitral and/or tricuspid valve regur...
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Paying less for Pimobendan
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1
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They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
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2
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The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Vetmedin 1.5 mg/ml Oral Solution for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
cardiomyopathy or valvular insufficiency (mitral and/or tricuspid valve
regurgitation).
For the treatment of dilated cardiomyopathy in the preclinical stage
(asymptomatic with an increase in left ventricular end-systolic and end-diastolic
diameter) in Doberman Pinschers following echocardiographic diagnosis of
cardiac disease (see sections 4.4 and 4.5).
For the treatment of dogs with myxomatous mitral valve disease (MMVD) in the
preclinical stage (asymptomatic with a systolic mitral murmur and evidence of
increased heart size) to delay the onset of clinical symptoms of heart failure
(see sections 4.4 and 4.5).
which an improvement in cardiac output cannot be achieved for functional or
anatomical reasons (e.g., aortic stenosis).
Issued: March 2025
AN: 01625/2023
Since pimobendan is metabolised mainly via the liver, it should not be used in
dogs with severe impairment of liver function.
Do not use in cases of hypersensitivity to pimobendan or to any of the
excipients.
Rare
(1 to 10 animals / 10,000
animals treated):
- Vomiting
, diarrhoea
- Anorexia
, lethargy
- Increased heart rate
1,3
- Increase in mitral valve regurgitation
Very rare
(< 1 animal / 10,000 animals
treated, including isolated
reports):
- Mucosal petechiae
,
haemorrhages(subcutaneous)
1. Dose-dependent effects that can be avoided by reducing the dose.
2. Transient effects.
3. A mild, dose-dependent, positive chronotropic effect can occur that can be avoided by
reducing dose.
4. Observed during chronic pimobendan treatment in dogs with mitral valve disease.
5. Potential effects on primary haemostasis may be observed during treatment. These signs
disappear when the treatment is withdrawn. A relationship with pimobendan has not been
clearly established.
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or its local
representative or the Veterinary Medicines Directorate via the national reporting
system (https://www.gov.uk/report-veterinary-medicine-problem). See also
section 16 of the package leaflet for contact details.
with atrial fibrillation or sustained ventricular tachycardia.
The product has not been tested in cases of asymptomatic myxomatous mitral
valve disease in dogs with significant supraventricular and/or ventricular
tachyarrhythmia.
Special precautions for use in animals
In dogs with existing diabetes mellitus, blood glucose should be tested regularly
during treatment with pimobendan.
For use in the preclinical stage of dilated cardiomyopathy (asymptomatic with
an increase in left ventricular end-systolic and end-diastolic diameter), a
diagnosis should be made by means of a comprehensive cardiac examination
(incl. echocardiographic examination and possibly Holter monitoring).
For use in the preclinical stage of myxomatous mitral valve disease (stage B2,
according to ACVIM consensus: asymptomatic with mitral murmur ≥
cardiomegaly due to myxomatous mitral valve disease), a diagnosis should be
made by means of a comprehensive physical and cardiac examination which
should include echocardiography or radiography where appropriate.
Monitoring of cardiac function and morphology is recommended in animals
treated with pimobendan.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Accidental ingestion, especially by a child, may lead to the occurrence of
tachycardia, orthostatic hypotension, flushing of the face and headaches.
Do not leave a filled syringe unattended.
This product may cause eye or skin irritation. Avoid skin and eye contact.
In case of accidental eye or skin contact, immediately rinse thoroughly with
water.
In case irritation develops or if accidental ingestion occurs, seek medical advice
immediately and show the package leaflet or the label to the physician.
People with known hypersensitivity to pimobendan should avoid contact with
the product.
Do not eat, drink, or smoke while handling the product.
Wash hands after use.
Issued: March 2025
AN: 01625/2023
Special precautions for the protection of the environment
Not applicable.
ouabain (strophanthin) and pimobendan was observed. The pimobendan-
Issued: March 2025
AN: 01625/2023
induced increase in cardiac contractility is attenuated by the calcium
antagonists verapamil and diltiazem and by the β-antagonist propranolol.
clearly established.
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or its local
representative or the Veterinary Medicines Directorate via the national reporting
system (https://www.gov.uk/report-veterinary-medicine-problem). See also
section 16 of the package leaflet for contact details.
4.7 Use during pregnancy, lactation or lay
Laboratory studies in rats and rabbits have not produced any evidence of
teratogenic or foetotoxic effects. However, these studies have shown evidence
of maternotoxic and embryotoxic effects at high doses and have also shown
that pimobendan is excreted into milk. The safety of the product has not been
assessed in pregnant or nursing bitches. The product should only be
administered to pregnant or lactating bitches in accordance with the benefit/risk
assessment conducted by the responsible veterinarian.
4.8 Interaction with other medicinal products and other forms of interaction
In
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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