Vetmedin 1.25 mg Chewable Tablets for Dogs
Active ingredient: Pimobendan
Form
Chewable
Species
Manufacturer
Boehringer Ingelheim Vetmedica GmbH
VMD MA No.
04491/3030
What it's used for
For the treatment of dilated cardiomyopathy in the preclinical stage (asymptomatic with an increase in left ventricular end-systolic and end-diastolic diam...
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-
1
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They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
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2
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Vetmedin 1.25 mg Chewable Tablets for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
with an increase in left ventricular end-systolic and end-diastolic diameter) in
Doberman Pinschers following echocardiographic diagnosis of cardiac disease.
AN: 01122/2025Page 2 of 7
For the treatment of dogs with myxomatous mitral valve disease (MMVD) in the
preclinical stage (asymptomatic with a systolic mitral murmur and evidence of
increased heart size) to delay the onset of clinical symptoms of heart failure.
Determine the bodyweight accurately before treatment to ensure correct dosage.
The dose should be administered and within the dose range of 0.2 mg to 0.6 mg
pimobendan/kg bodyweight, divided into two daily doses. The preferable daily dose is
0.5 mg/kg bodyweight, divided into two daily doses (0.25 mg/kg bodyweight each)
approximately 12 hours apart. Each dose should be given approximately 1 hour
before feeding.
This corresponds to:
One 1.25 mg chewable tablet in the morning and one 1.25 mg chewable tablet in the
evening for a bodyweight of 5 kg.
One 2.5 mg chewable tablet in the morning and one 2.5 mg chewable tablet in the
evening for a bodyweight of 10 kg.
One 5 mg chewable tablet in the morning and one 5 mg chewable tablet in the
evening for a bodyweight of 20 kg.
1.25 mg chewable
tablet
2.5 mg
chewable
tablet
5 mg chewable tablet
Bodyweight
Morning EveningMorning Eveni
ng
Morning Evening5 kg1110 kg1120 kg11
Chewable tablets can be halved at the score line provided, for dosage accuracy,
according to the bodyweight. Use any divided tablet at the next administration time.
The veterinary medicinal product may be combined with a diuretic, e.g., furosemide.
improvement in cardiac output cannot be achieved for functional or anatomical
reasons (e.g. aortic stenosis).
Since pimobendan is metabolised mainly via the liver, it should not be used in dogs
with severe impairment of liver function.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Rare
(1 to 10 animals / 10,000
animals treated):
- Vomiting
, diarrhoea
- Anorexia
, lethargy
- Increased heart rate
1,3
,
increase in mitral valve
regurgitation
Very rare
(< 1 animal / 10,000 animals
treated, including isolated
reports):
- Mucosa petechiae
, haemorrhages
(subcutaneous)
1
These effects are dose-dependent and can be avoided by reducing the dose.
Transient
Due to a slight positively chronotropic effect.
Observed during chronic pimobendan treatment in dogs with mitral valve
disease.
A relationship with pimobendan has not been clearly established, signs
disappear when the treatment is withdrawn.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
in Dobermans with atrial fibrillation or sustained ventricular tachycardia.
The veterinary medicinal product has not been tested in cases of asymptomatic
myxomatous mitral valve disease in dogs with significant supraventricular and/or
ventricular tachyarrhythmia.
Special precautions for safe use in the target species:
The blood glucose should be tested regularly during treatment in dogs with existing
diabetes mellitus.
For use in the preclinical stage of dilated cardiomyopathy (asymptomatic with an
increase in left ventricular end-systolic and end-diastolic diameter), a diagnosis
should be made by means of a comprehensive cardiac examination (incl.
echocardiographic examination and possibly Holter monitoring).
For use in the preclinical stage of myxomatous mitral valve disease (stage B2,
according to ACVIM consensus: asymptomatic with mitral murmur ≥3/6
cardiomegaly due to myxomatous mitral valve disease), a diagnosis should be made
by means of a comprehensive physical and cardiac examination which should
include echocardiography or radiography where appropriate.
Monitoring of cardiac function and morphology is recommended in animals treated
with pimobendan.
The chewable tablets are flavoured. In order to avoid any accidental ingestion, store
tablets out of reach of the animals.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
Wash hands after use.
AN: 01122/2025Page 3 of 7
Advice to doctors: accidental ingestion, especially by a child, may lead to the
occurrence of tachycardia, orthostatic hypotension, flushing of the face and
headaches.
Close bottle tightly with cap directly after removal of the required number of tablets.
Special precautions for the protection of the environment:
Not applicable.
and pimobendan was observed. The pimobendan-induced increase in cardiac
contractility is attenuated by the calcium antagonists verapamil and diltiazem and by
the β-antagonist propranolol.
AN: 01122/2025Page 4 of 7
Keep the bottle tightly closed in order to protect from moisture.
AN: 01122/2025Page 7 of 7
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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