Tramadog, 50 mg/ml, Solution for Injection for Dogs
Active ingredient: Tramadol hydrochloride
Form
Injection
Species
Manufacturer
Domes Pharma
VMD MA No.
54982/4009
What it's used for
For the reduction of mild postoperative pain.
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Tramadog, 50 mg/ml, Solution for Injection for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
Animals should be weighed to establish an accurate body weight prior to calculation
of the appropriate treatment dose.
Route
Dose of
tramadol (as
hydrochloride)
Dose product
IM, IV 2-4 mg/kg bw *0.04-0.08 ml/kg bw
Comments
*On the basis of the intensity of pain, repeat doses can be
administered every 6 to 8 hours (3-4 times daily). The
recommended maximum daily dose is 16 mg/kg.
Intravenous administration must be carried out very slowly.
As the individual response to tramadol is variable, and depends partly on the dosage,
the age of the patient, individual differences in pain sensitivity and general condition,
the optimal dosing regimen should be individually tailored using the above dose and
re-treatment interval ranges. In the event of the product failing to provide adequate
analgesia by 30 minutes following administration or for the duration of any planned
re-treatment interval, a suitable alternative analgesic should be used.
Do not use in dogs receiving concomitant treatment with tricyclic antidepressants,
MAO inhibitors or serotonin reuptake inhibitors.
Do not use in animals with epilepsy.
veterinary medicinal product. In rare cases (more than 1 but less than 10 animals in
10,000 animals treated) hypersensitivity can occur. In cases of hypersensitivity
reactions the treatment should be discontinued. In the event that a reaction due to
use of the medicinal product is observed, withdrawal of treatment is recommended.
be due to individual differences in the metabolism of the drug to the primary active
metabolite O-desmethyltramadol. In some dogs (non-responders), this may result in
the product failing to provide analgesia. Dogs should therefore be monitored regularly
to ensure sufficient efficacy.
Unlimited renewal : October 2022
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Special precautions for use in animals
Use with caution in dogs with renal or hepatic impairment. In dogs with hepatic
impairment the metabolism of tramadol to the active metabolites may be decreased
which may reduce the efficacy of the product. One of the active metabolites of
tramadol is renally excreted and therefore in dogs with renal impairment the dosing
regimen used may need to be adjusted. Renal and hepatic function should be
monitored when using this product. See also section 4.8.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
People with known hypersensitivity to tramadol or any of the excipients should avoid
contact with the veterinary medicinal product.
Tramadol may cause nausea and dizziness following injection. Avoid accidental self-
injection. If you develop symptoms following exposure, seek medical advice and
show the package leaflet or the label to the physician. However, DO NOT DRIVE as
sedation may occur.
There is inadequate evidence available on the safety of tramadol in human
pregnancy. Pregnant women and women of childbearing age should therefore take
great care when handling this product and, in the event of exposure, seek medical
advice immediately.
system depressants may potentiate the CNS and respiratory depressant effects.
Tramadol may cause convulsions and intensify the effect of drugs that lower the
convulsive threshold.
When the product is administered together with medicinal products with a sedative
effect, the duration of sedation may be increased.
Drugs that inhibit (e.g. cimetidine and erythromycin) or induce (e.g. carbamazepine)
CYP450 mediated metabolism may have an effect on the analgesic effect of
tramadol. The clinical relevance of these interactions has not been studied in dogs.
The combination with mixed agonist/antagonists (e.g. buprenorphine, butorphanol)
and tramadol is not advisable, because the analgesic effect of a pure agonist may be
theoretically reduced in such circumstances.See also section 4.3.
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Related Conditions
Other Products Containing Tramadol hydrochloride
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
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Tralieve 50 mg/ml Solution for Injection for Dogs
POM-VLe Vet Beheer B.V.
Tralieve 80 mg Chewable Tablets for Dogs
POM-VDechra Regulatory B.V.
Tralieve 80 mg Chewable Tablets for Dogs
POM-VDechra Regulatory BV
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