POM-V Prescription Required

Sputolosin Oral Powder 5 mg/g

Active ingredient: Dembrexine Hydrochloride Monohydrate

Form

Powder

Species

Horses

Manufacturer

Boehringer Ingelheim Animal Health UK Ltd

VMD MA No.

08327/5065

What it's used for

The product is indicated for the symptomatic treatment of acute, sub-acute and chronic respiratory disease of the upper and lower respiratory tract, where...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Dembrexine Hydrochloride Mon...

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Sputolosin Oral Powder 5 mg/g — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

The product is indicated for the symptomatic treatment of acute, sub-acute and chronic
respiratory disease of the upper and lower respiratory tract, where an abnormal amount
of mucus of increased viscosity is present..

For oral administration in the food at a dose rate of 0.3 mg dembrexine per kg bodyweight
twice daily: for example, for a 500kg horse, 30 g (6 level measures) of powder twice daily.
For small horses, ponies and foals the dose is administered pro rata according to the
bodyweight, i.e. at a rate of 2 level measures per 170 kg bodyweight.
Add to the feed immediately prior to administration. Discard any remaining medicated feed.
An improvement in clinical signs is usually seen within five days. Treatment should be
continued until complete remission occurs (usually a total period of 12 to 14 days) but should
not exceed 28 days. The horse's condition should be reassessed after this period before any
further treatment is proposed.
In cases complicated by the presence of micro-organisms or where pyrexia is present, the
simultaneous use of suitable chemotherapeutic agent is recommended.

Do not use in animals known to be hypersensitive to the active substance.

None known.

None known.

(i) Special precautions for use in animals
None known.
(ii) Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Care/precautions should be taken when using this product to avoid skin contact, eye
contact and/or inhalation of the dust. Medical advice should be sought if you feel unwell
after using this product.

Revised: August 2025
MA split from NI following AN: 01291/2025

None known.

Do not store above 25C. Store in a dry place.

Meat and offal: 1 day
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.