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AVM-GSL Over the Counter Companion Animal

Rofectan Plus XL Tablets For Dogs

Active ingredients: Febantel, Praziquantel, Pyrantel Embonate

Form

Tablet

Species

Dogs

Manufacturer

C&H Generics Ltd

VMD MA No.

40162/4035

What it's used for

In adult dogs: For the treatment of mixed infections with roundworms, hookworms, whipworms, and tapeworms of the following species: Roundworms (Nematodes):...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Clinical information

Rofectan Plus XL Tablets For Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

In adult dogs:
For the treatment of mixed infections with roundworms, hookworms,
whipworms, and tapeworms of the following species:
Roundworms (Nematodes):
Ascarids (adult and late immature forms): Toxocara canis, Toxascaris leonina.
Hookworms (adults): Uncinaria stenocephala, Ancylostoma caninum.
Whipworms (adults): Trichuris vulpis.

Amended pages: February 2021
AN: 02194/2017
Tapeworms (Cestodes):
Adult and immature forms of: Echinococcus species (E. granulosus, E.
multilocularis), Taenia (T. hydatigena, T. pisiformis, T. taeniformis),
Dipylidium caninum.
For oral administration only.
To ensure administration of a correct dose, body weight should be determined
as accurately as possible.
Dosage:
1 tablet per 35 kg bodyweight.
This is equivalent to 15 mg febantel, 14.4 mg pyrantel embonate and 5 mg
praziquantel per kilo bodyweight.

Amended pages: February 2021
AN: 02194/2017
It is important to follow the treatment recommendations as presented here. Do
not deviate from the recommendations without the advice of your veterinary
surgeon.
Dosage table:
Bodyweight (kg)Tablets17.5kg½ >17.5-35.0 kg1 >35.0-52.5 kg1 ½ >52.5-70 kg2
Administration and Duration of Treatment
Not for use in dogs weighing less than 17.5 kg
The tablets can be given directly to the dog or disguised in food. No starvation
is needed before or after treatment.
For routine worm control adult dogs should be treated with a single dose every
3 months.
For the control of Toxocara, nursing bitches should be dosed 2 weeks after
giving birth and every two weeks until weaning.
In case of suspected heavy roundworm infestation, please contact your
veterinary surgeon for diagnosis and treatment recommendations.
If there is a risk of re-infestation (see section 4.4), the advice of a veterinarian
should be sought regarding the need for and the frequency of repeat
administration.
Do not use in cases of hypersensitivity to the active substances or to any of the
excipients
Do not use simultaneously with piperazine compounds as piperazine may block
the action of pyrantel embonate contained in this product. Other worming
products may contain piperazine.
Do not use simultaneously with other deworming products without veterinary
advice.
Do not exceed the stated dose.
In very rare cases mild and transient digestive tract disorders such as vomiting
and/or diarrhoea may occur. In individual cases these signs can be
accompanied by nonspecific signs such as lethargy, anorexia, or hyperactivity.
The frequency of adverse reactions is defined using the following convention:
- Very common (more than 1 in 10 animals treated displaying adverse
reaction(s))
- Common (more than 1 but less than 10 animals in 100 animals treated)
- Uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- Rare (more than 1 but less than 10 animals in 10,000 animals treated)
- Very rare (less than 1 animal in 10,000 animals treated, including isolated
reports).
Fleas serve as intermediate hosts for one common type of tapeworm –
Dipylidium caninum. Tapeworm infestation is certain to reoccur unless control
of intermediate hosts such as fleas, mice, etc. is undertaken.
Dogs should also be prevented from scavenging or hunting as part of measures
to prevent tapeworm reinfestation.
If your dog receives other veterinary medicinal products, check with a veterinary
surgeon or pharmacist before using this product.
Parasite resistance to any particular class of anthelmintic may develop following
frequent, repeated use of an anthelmintic of that class.

Special precautions for use in animals
Do not exceed the stated dose, especially when treating pregnant bitches.
To ensure administration of a correct dose, body weight should be determined
as accurately as possible.
Special precautions to be taken by the person administering the
veterinary medicinal product to animals
In case of accidental ingestion, seek medical advice and show the package
leaflet to the physician.
In the interests of good hygiene, persons administering the tablets directly to
the dog, or by adding them to the dog’s food, should wash their hands
afterwards.
Other precautions
Echinococcosis represents a hazard for humans. As Echinococcosis is a
notifiable disease to the World Organisation for Animal Health (OIE), specific
guidelines on the treatment and follow-up, and on the safeguard of persons,
need to be obtained from the relevant competent authority.

Amended pages: February 2021
AN: 02194/2017
Do not use simultaneously with piperazine compounds as the anthelmintic
effects of pyrantel and piperazine may be antagonized (see section 4.3).
Concurrent use with other cholinergic compounds (e.g. neostigmine, propoxur,
and bethanechol) can lead to toxicity.
This veterinary medicinal product does not require any special temperature
storage conditions.
Keep the blister in the outer carton in order to protect from light.
Each time an unused half tablet is stored, it should be returned to the open
blister space and the blister inserted back into the outer carton.
Administration and Duration of Treatment
Not for use in dogs weighing less than 17.5 kg
The tablets can be given directly to the dog or disguised in food. No starvation
is needed before or after treatment.
For routine worm control adult dogs should be treated with a single dose every
3 months.
For the control of Toxocara, nursing bitches should be dosed 2 weeks after
giving birth and every two weeks until weaning.
In case of suspected heavy roundworm infestation, please contact your
veterinary surgeon for diagnosis and treatment recommendations.
If there is a risk of re-infestation (see section 4.4), the advice of a veterinarian
should be sought regarding the need for and the frequency of repeat
administration.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
The combination of praziquantel, pyrantel embonate and febantel is well
tolerated in dogs. In safety studies, a single dose of 5 times the recommended
dose or greater gave rise to occasional vomiting.
4.11 Withdrawal period(s)
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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