POM-V Prescription Required

Relaquine 35 mg/ml Oral Gel for Horses

Active ingredient: Acepromazine

Form

Gel

Species

Horses

Manufacturer

Floris Holding B.V.

VMD MA No.

56190/3001

What it's used for

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Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Acepromazine

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Relaquine 35 mg/ml Oral Gel for Horses — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

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Prefilled syringe
The veterinary medicinal product is contained within a 10 ml or 15 ml polyethylene syringe.
The plunger has a locking ring which should be adjusted to provide the volume required in
accordance with the dosage guidelines. 1.0 ml intervals are printed on the syringe plunger,
but it is also possible to dose at 0.5 ml intervals.

Before first use of the syringe, turn the locking ring clockwise until aligned with the 0.0 ml
mark (side of the ring facing the barrel). Turn the locking ring anti-clockwise will move the
ring backwards. Turn the locking ring backwards until the left side of the locking ring lines
up with the volume of the oral gel to be administered.
Place the syringe in the animal's mouth and expel the required dose into the cheek pouch.
The gel may also be mixed with food.
Glass bottle
The veterinary medicinal product is filled into 10, 15, 20, 30 and 50 ml glass bottles with
CRC closure and supplied with a 5 ml syringe with a dose graduation allowing accurate
dosing of 0.1 or 0.2 ml. Withdraw the appropriate dose from the bottle using the supplied
syringe. The syringe is brought into the animal's mouth and the appropriate dose is
expelled into the animal's cheek.
The gel may also be mixed with food.
Amount(s) to be administered
Moderate sedation: 0.15 mg acepromazine per kg bodyweight
Dosage guidelines:
Bodyweight
(kg)
200300400450500600Dose (ml)1.01.51.52.02.52.5
The above dosage information is provided as a guideline. The dose may be varied to
administer between 0.5 and 1.5 times the above recommendation depending on the level
of sedation required, i.e. for mild sedation, administer half the recommended dose and for
deeper sedation, administer 1½ times the recommended dose.

Do not use in cases of post-traumatic shock or hypovolaemia.
Do not use in animals in a state of severe emotional excitation.
Do not use in animals with epilepsy.
Do not use in pregnant or lactating mares.
Do not use in animals with heart failure.
Do not use in animals with haematological disorders/coagulopathies.
Do not use in animals suffering from hypothermia.
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Do not use in neonates.

Horse:
Rare
(1 to 10 animals / 10,000 animals
treated):
Excitation
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Low blood pressure
,
Hypothermia
, Hyperthermia
Decreased red blood cell count
, Decreased
haemoglobin
, Low platelet count
, Leucopenia
Infertility
, Penile prolapse
, Paraphimosis
, Priapism
Aggression
, Generalized central nervous system
stimulation
Prolapse of the nictitating membrane
Paradoxical reaction
Since acepromazine decreases sympathetic nervous system tone, a transient drop in
blood pressure may occur after administration.
Inhibition of temperature regulation.
Transient.
Because it increases prolactin secretion, the administration of acepromazine may lead to
disturbances in fertility.
Due to the relaxation of the retractor penis muscles. Retraction of the penis should be
visible within two to three hours. If this does not take place, it is advised to contact a
veterinary surgeon. Lack of retraction is of particular concern in breeding stallions.
Acepromazine has caused paraphimosis sometimes in sequel to priapism.
Contradictory clinical signs
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

Sedation lasts for approximately six hours, although the actual time and depth of sedation
are very dependent on the status of the individual animal.
Increasing the dosage above that recommended
effects but no greater sedation.

Special precautions for safe use in the target species:
In stallions, the lowest dose range is indicated to minimise prolapse of the penis.
The veterinary medicinal product should be used with caution and with reduced dosage in
the case of cardiac or hepatic disease or in debilitated, hypovolemic or anaemic animals.
Acepromazine has negligible analgesic effects. Painful activities should be avoided when
handling tranquillized animals.
Tranquillized horses should be kept in a calm place and sensorial stimuli should be
avoided as far as possible.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Wash hands and exposed skin thoroughly after use.
Persons with sensitive skin or in continuous contact with the veterinary medicinal product
are advised to wear impermeable gloves.
Avoid eye contact. In case of accidental eye contact, rinse the eye for 15 minutes with
clean water and consult a physician if irritation persists.
In case of accidental ingestion, seek medical advice immediately and show the package
leaflet or the label to the physician but, DO NOT DRIVE as sedation can occur.
Special precautions for the protection of the environment:
Not applicable.
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Acepromazine potentiates the action of centrally depressant drugs.
Simultaneous administration, or administration to horses recently treated with
organophosphates should be avoided, since these molecules enhance the toxic effects of
acepromazine. Since acepromazine decreases sympathetic nervous system tone,
simultaneous treatment with blood pressure lowering products should not take place.
Antacids may cause a decrease in the gastrointestinal absorption of acepromazine after
oral administration.
AN: 03162/2023 & 03152/2023Page 4 of 7Opiates may enhance the hypotensive effects of acepromazine.

Do not store above 25 °C.
Protect from frost.
Protect from light.
After use, replace cap on syringe. Keep the broached syringe in the original carton and
store in a dry place.

Not authorised for use in horses intended for human consumption.
Not authorised for use in animals producing milk for human consumption.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.