POM-V Prescription Required

Quadrisol 100 mg/ml Oral Gel for Horses

Active ingredient: Vedaprofen

Form

Gel

Species

Horses

Manufacturer

Grovet B.V.

VMD MA No.

51010/5000

What it's used for

anticipated surgical trauma, Quadrisol can be given prophylactically at least 3 hours prior to elective surgery.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Vedaprofen

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Quadrisol 100 mg/ml Oral Gel for Horses — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

anticipated surgical trauma, Quadrisol can be given prophylactically at least 3 hours
prior to elective surgery.

Twice daily administration. An initial dose of 2 mg/kg (2.0 ml/100 kg) is followed by
a maintenance dose of 1 mg/kg (1.0 ml/100 kg) given every 12 hours. Treatment
can be continued for a maximum of 14 consecutive days. In case of prophylactic
treatment, a maximum duration of treatment of 7 consecutive days is sufficient.
To ensure a correct dosage, body weight should be determined as accurately as
possible.
The gel is administered orally by inserting the nozzle of the syringe through the
interdental space and depositing the required amount of gel on the back of the
tongue. Before administration, the syringe should be adjusted to the calculated
dosage by setting the ring on the plunger.
It is advisable to administer the product before feeding.
In cases of anticipated surgical trauma, the veterinary medicinal product can be
given prophylactically at least 3 hours prior to elective surgery.

Do not use in animals suffering from alimentary tract disorders, impaired heart, liver
and kidney function.
Do not use in foals under the age of 6 months.
Do not use in lactating mares.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.

Horses:
Undetermined frequency
(cannot be estimated from the
available data):
Digestive tract disorder
Soft stool
Urticaria
Lethargy
1
Lesions in the alimentary tract.
Reversible.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian,
to either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

Horses intended for racing and competition should be treated according to local
requirements. Appropriate precautions must be taken for such horses to ensure
compliance with competition regulations. In case of doubt, it is advisable to test the
urine.

Special precautions for safe use in the target species:
If side effects occur, treatment should be discontinued. Horses with oral lesions
should be assessed clinically and the attending veterinarian should take a decision
as to whether treatment should be continued. If oral lesions persist, treatment should
be discontinued.
Horses should be monitored for oral lesions during treatment. Avoid use in any
dehydrated, hypovolaemic or hypotensive animals, as there may be potential risk of
increased renal toxicity
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.

Other NSAIDs, diuretics and substances with high protein binding may compete for
binding and lead to toxic effects. Quadrisol must not be given with other NSAIDs or
glucocorticosteroids.

This veterinary medicinal product does not require any special storage conditions.

Meat and offal: 12 days.
Not authorised for use in animals producing milk for human consumption.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.