Profender 50 mg/10 mg Modified-Release Tablets for Medium Dogs

Parasite resistance to any particular class of anthelmintic may develop following
frequent, repeated use of an anthelmintic of that class.
Unnecessary use of antiparasitics or use deviating from the instructions given in the
SPC may increase the resistance selection pressure and lead to reduced efficacy.
The decision to use the veterinary medicinal product should be based on
confirmation of the parasitic species and burden, or of the risk of infection based on
its epidemiological features, for each individual animal.
The possibility that other animals in the same household can be a source of re-
infection with roundworms and tapeworms should be considered, and these should
be treated as necessary with an appropriate veterinary medicinal product.

Special precautions for safe use in the target species:
Administer only to fasted dogs. For example: Overnight fasting if the dog is to be
treated in the morning. No food should be given until 4 hours after treatment.
When D. caninum infection is present, concomitant treatment against intermediate
hosts such as fleas and lice should be considered to prevent reinfection.
No studies have been performed with severely debilitated dogs or individuals with
seriously compromised kidney or liver function. Therefore, the veterinary medicinal
product should only be used in such animals according to a benefit/risk assessment
by the responsible veterinarian.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
In the interests of good hygiene, wash your hands after administering the tablets to
the dog.
In case of accidental ingestion, especially in the case of children, seek medical
advice immediately and show the package leaflet or the label to the physician.
Echinococcosis represents a hazard for humans. As Echinococcosis is a notifiable
disease to the World Organisation for Animal Health (WOAH), specific guidelines on
the treatment and follow-up, and on the safeguard of persons, need to be obtained
from the relevant competent authority.
Special precautions for the protection of the environment:
Not applicable.