POM-V Prescription Required

Peptizole 370 mg/g Oral Paste for Horses

Active ingredient: Omeprazole

Form

Paste

Species

Horses

Manufacturer

Norbrook Laboratories Limited

VMD MA No.

02000/4389

What it's used for

AN: 00736/2025 & 01372/2025

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Omeprazole

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Peptizole 370 mg/g Oral Paste for Horses — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

AN: 00736/2025 & 01372/2025

For oral administration.
Prevention of gastric ulcers: one administration per day during 28 consecutive days
at a minimum dose rate of 1 mg omeprazole per kg body weight.
It is recommended to associate use of the product with changes of husbandry and
training practices. Please see also the text under section 3.5.
Each syringe contains 4 individual daily doses for horses weighing 272 - 544 kg.
Please refer to the following dosage chart for help in determining the correct dosage
for your horse.
Omeproshield 370 mg/g oral paste for horses
dosage chart
Horse weightDosage*< 272 kgConsult a veterinarian272 kg - 544 kg1 dose per day> 544 kg2 doses per day*For a duration of 28 consecutive days
Instructions for use:
1. To set the syringe plunger, while holding plunger, turn the knurled ring on the
plunger one quarter turn to the left and slide the knurled ring along the plunger
shaft so that the side nearest the barrel is at the appropriate daily dose marking,
aligning the arrow on the plunger with the notch on the ring.
AN: 00736/2025 & 01372/2025
2. Lock the ring in place by making one quarter turn to the right. Ensure it is locked
(it should no longer slide). Make sure the horse’s mouth contains no feed before
administration.
3. Remove syringe tip cover.
4. Insert syringe into the corner of the horse’s mouth.
5. Depress the plunger until it stops at the dose ring. The entire dose should be
deposited on the back of the tongue or deep in the cheek pouch.
6. Horses should be observed briefly to assure no part of the dose is lost or
rejected.
If any of the dose is lost, re-dosing is recommended.
Replace cap after use.

Do not use in mares producing milk for human consumption.
See section 3.5.

Horses:
None known.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
AN: 00736/2025 & 01372/2025

None.

Special precautions for safe use in the target species:
Not recommended for animals under 4 weeks of age or weighing less than 70 kg
bodyweight.
Stress (including high performance training and competition), feeding, management
and husbandry practices may be associated with the development of gastric
ulceration in horses. Individuals responsible for the well-being of horses should
consider reducing the ulcerogenic challenge by modifying husbandry practices to
achieve one or more of the following: reduced stress, reduced fasting, increased
intake of roughage and access to grazing.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
As this product may cause hypersensitivity, avoid direct contact with skin and eyes.
Personal protective clothing consisting of impervious gloves should be worn when
handling the product. Do not eat or drink when handling and administering the
product. Wash hands or any exposed skin after use. In case of contact with eyes,
wash immediately with clean running water and seek medical advice. Persons
developing a reaction after contact with the product should avoid handling the
product in future.
Special precautions for the protection of the environment:
Not applicable.

Omeprazole may delay the elimination of warfarin. No other interaction with
medicines routinely used in the treatment of horses is expected, although interaction
with drugs metabolised by liver enzymes cannot be excluded.

Do not store above 30°C. Replace cap after use.

Meat and offal: 1 day.
Not authorised for use in mares producing milk for human consumption.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.