OsteoCox 227 mg Chewable Tablets for Dogs

None.

Special precautions for safe use in the target species:
The recommended dose should not be exceeded.
Use in very young animals, or animals with suspected or confirmed impairment
of renal, cardiac or hepatic function may involve additional risk. If such use
cannot be avoided, those dogs require careful veterinary monitoring.
Avoid use in dehydrated, hypovolaemic or hypotensive animals, as there is a
potential risk of increased renal toxicity. Concurrent administration of potentially
nephrotoxic drugs should be avoided.
Use this product under strict veterinary monitoring where there is a risk of
gastrointestinal bleeding, or if the animal previously displayed intolerance to
NSAIDs. Renal and/or hepatic disorders have been reported in very rare cases
in dogs administered the recommended treatment dose. It is possible that a
proportion of such cases had sub-clinical renal or hepatic disease prior to the
commencement of therapy. Therefore, appropriate laboratory testing to
establish baseline renal or hepatic biochemistry parameters is recommended
prior to and periodically during administration.
The treatment should be discontinued if any of these signs are observed:
repeated diarrhoea, vomiting, faecal occult blood, sudden weight loss, anorexia,
lethargy, degradation of renal or hepatic biochemistry parameters.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
This product can cause hypersensitivity (allergic) reactions. People with a known
hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) should avoid
contact with the product.
This product may be harmful following accidental ingestion.
Care should be taken to avoid accidental ingestion.
In order to prevent children from accessing the product, tablets should be
administered and stored out of sight of children.
Divided tablets should be returned to the open blister and inserted into the outer
carton.
Laboratory studies in rats and rabbits have shown evidence that firocoxib has the
potential to effect reproduction and to induce malformation in foetuses. Pregnant
women or those attempting to conceive should administer the product with caution.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
Wash hands after use of the product.
Special precautions for the protection of the environment:
Not applicable.