POM-V Prescription Required Companion Animal

Oncept IL-2

Active ingredient: Feline interleukin-2 recombinant canarypox virus

Form

Injection

Species

Cats

Manufacturer

Boehringer Ingelheim Vetmedica GmbH

VMD MA No.

04491/5039

What it's used for

years.

Full indications, dosage and side effects ↓

View official SPC (PDF)

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1

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2

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Prescription required

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Clinical information

Oncept IL-2 — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

years.

After reconstitution of the lyophilisate with the solvent, shake gently and administer
five injections (each approximately 0.2 ml) around the tumour excision site: one
injection at each corner and one injection at the centre of a 5 cm x 5 cm square
centred on the middle of the surgical scar.
Treatment course: 4 administrations at 1-week intervals (day 0, day 7, day 14, day
21) followed by
2 administrations at 2-week intervals (day 35, day 49).
Start the treatment course the day before radiation therapy, preferably within one
month after surgical excision.

None.

Cats:
Very common
(>1 animal / 10 animals treated):
Injection site pain
Injection site swelling
Injection site scratching
Common
(1 to 10 animals / 100 animals treated):
Apathy
Hyperthermia
2,3
Moderate, usually disappears spontaneously within 1 week.
Transient.
Above 39.5 °C.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian,
to either the marketing authorisation holder <or its local representative> or the
national competent authority via the national reporting system. See the package
leaflet for respective contact details.

Use of the recommended mode of administration in 5 injection points is important for
achieving efficacy of the product; injection in 1 point may lead to reduced efficacy
(see section 4.9).
Efficacy has only been tested in conjunction with surgery and radiotherapy; therefore
the treatment should be conducted according to treatment course described in
section 4.9.
Efficacy has not been tested in cats with metastasis or lymph node involvement.
As safety and efficacy of repetition of the treatment to treat fibrosarcoma recurrence
have not been investigated, repetition of the treatment should be considered by the
veterinarian taking into account the benefit-risk balance.
Efficacy of the treatment has not been investigated beyond 2 years following
treatment.

Special precautions for safe use in the target species:
Not applicable.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Canarypox recombinants are known to be safe for humans. Mild local and/or
systemic adverse eventsrelated to the injection itself may be observed transitorily.
Moreover feline IL-2 has been shown to have very low biological activity on human
leukocytes compared to human IL-2. In case of accidental self-injection, seek
medical advice immediately and show the package leaflet or the label to the
physician.
Special precautions for the protection of the environment:
Not applicable.

No information is available on the safety and efficacy of this immunological
veterinary medicinal product when used with any other veterinary medicinal product.
A decision to use this immunological veterinary medicinal product before or after any
other veterinary medicinal product therefore needs to be made on a case by case
basis.

Store and transport refrigerated (2 °C-8 °C).
Store in the original package.
Protect from light.
Do not freeze.

Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.