POM-V Prescription Required Companion Animal

Nelio 5 mg Tablet for Cats

Active ingredient: Benazepril Hydrochloride

Form

Tablet

Species

Cats

Manufacturer

Ceva Sante Animale

VMD MA No.

14966/5019

What it's used for

Dogs: Treatment of congestive heart failure. Cats: Reduction of proteinuria associated with chronic kidney disease.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Benazepril Hydrochloride

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Nelio 5 mg Tablet for Cats — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Dogs:
Treatment of congestive heart failure.
Cats:
Reduction of proteinuria associated with chronic kidney disease.

The veterinary medicinal product should be given orally once daily, with or without
food. The duration of treatment is unlimited.
The veterinary medicinal product tablets are flavoured and are taken voluntarily by
most cats.
Cats:
The veterinary medicinal product should be administered orally at a minimum dose of
0.5 mg (range 0.5-1.0) benazepril hydrochloride/kg body weight once daily according
to the following table:
Cat weight (kg)Number of tablets2.5 – 5.00.5>5. – 10.01
To ensure a correct dosage, body weight should be determined as accurately as
possible.
In case of use of half tablets: Put the remaining half of the tablet back into the blister
pocket and use for the next administration.
Instruction on how to divide the tablet: Put the tablet on an even surface, with its
scored side facing down (convex face up). With the tip of the forefinger, exert slight
vertical pressure on the middle of the tablet to break it along its width into halves.
Then, in order to obtain quarters, exert slight pressure on the middle of one half with
the forefinger to break it into two parts.

Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Do not use in cases of hypotension, hypovolaemia, hyponatraemia or acute renal
failure.
Do not use in cases of cardiac output failure due to aortic or pulmonary stenosis.
Do not use during pregnancy or lactation (section 3.7).

Cats:
Rare
(1 to 10 animals / 10,000
animals treated):
Diarrhoea, Emesis
Anorexia, Dehydration, Lethargy
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Elevated creatinine
Undetermined frequency
(cannot be estimated from the
available data):
Increased appetite, Weight gain
At the start of therapy, in cats with chronic kidney disease. A moderate increase in
plasma creatinine concentrations following administration of ACE inhibitors is
compatible with the reduction in glomerular hypertension induced by these agents,
and therefore is not necessarily a reason to stop therapy in the absence of other
signs.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.

Special precautions for safe use in the target species:
Efficacy and safety of benazepril have not been established in cats of weight less
than 2.5 kg.
No evidence of renal toxicity to the veterinary medicinal product has been observed
in cats during clinical trials, however, as is routine in cases of chronic kidney disease,
it is recommended to monitor plasma creatinine, urea and erythrocyte counts during
therapy.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Angiotensin converting enzyme (ACE) inhibitors have been found to affect the unborn
child during pregnancy in humans. Pregnant women should take special care to
avoid accidental oral exposure.
Wash hands after use.
In case of accidental oral ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.

In humans, the combination of ACE inhibitors and Non-Steroidal Anti-Inflammatory
Drugs (NSAIDs) can lead to reduced anti-hypertensive efficacy or impaired renal
function. The combination of the veterinary medicinal product and other anti-
hypertensive agents (e.g. calcium channel blockers, ß-blockers or diuretics),
anaesthetics or sedatives may lead to additive hypotensive effects. Therefore,
concurrent use of NSAIDs or other medications with a hypotensive effect should be
considered with care. Renal function and signs of hypotension (lethargy, weakness
etc) should be monitored closely and treated as necessary.
Interactions with potassium preserving diuretics like spironolactone, triamterene or
amiloride cannot be ruled out. It is recommended to monitor plasma potassium levels
when using the veterinary medicinal product in combination with a potassium sparing
diuretic because of the risk of hyperkalaemia.

Do not store above 25C.
Store in original package in order to protect from moisture.
Any part-used tablet should be returned to the opened blister and used within 72
hours.

To ensure a correct dosage, body weight should be determined as accurately as
possible.
In case of use of half tablets: Put the remaining half of the tablet back into the blister
pocket and use for the next administration.
Instruction on how to divide the tablet: Put the tablet on an even surface, with its
scored side facing down (convex face up). With the tip of the forefinger, exert slight
vertical pressure on the middle of the tablet to break it along its width into halves.
Then, in order to obtain quarters, exert slight pressure on the middle of one half with
the forefinger to break it into two parts.
3.10 Symptoms of overdose (and where applicable, emergency procedures,
and antidotes)
The veterinary medicinal product reduced erythrocyte counts in normal cats when
dosed at 10 mg/kg body weight once daily for 12 months, but this effect was not
observed at the recommended dose during clinical trials in cats.
Transient reversible hypotension may occur in cases of accidental overdose. Therapy
should consist of intravenous infusion with warm isotonic saline.
3.11.Special restrictions for use and special conditions for use, including
restrictions on the use of antimicrobial and antiparasitic veterinary medicinal
products in order to limit the risk of development of resistance
Not applicable.
3.12 Withdrawal periods
Not applicable.
4.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.