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POM-V Prescription Required Companion Animal

Nelio 20 mg Tablet for Dogs

Active ingredient: Benazepril Hydrochloride

Form

Tablet

Species

Dogs

Manufacturer

Ceva Sante Animale

VMD MA No.

14966/5021

What it's used for

Dogs: Treatment of congestive heart failure. Cats: Reduction of proteinuria associated with chronic kidney disease.

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Benazepril Hydrochloride

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Nelio 20 mg Tablet for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Dogs:
Treatment of congestive heart failure.
Cats:
Reduction of proteinuria associated with chronic kidney disease.
treatment is unlimited.
Dogs:
The product should be administered orally at a minimum dose of 0.25 mg
(range 0.25-0.5) benazepril hydrochloride/kg body weight once daily,
according to the following table:
Weight of dog (kg)Standard doseDouble dose>20-400.5 tablet1 tablet>40-600.75 tablet1 ½ tablets>60-801 tablet2 tablets
The dose may be doubled, still administered once daily, to a minimum dose of 0.5
mg/kg (range 0.5-1.0), if judged clinically necessary and advised by the veterinary
surgeon.
In case of use of quarters or half tablets: Put the remaining quantity of the tablet
back into the blister pocket and use for the next administration.
The tablets are flavoured and may be taken spontaneously by dogs, but can also be
administered directly into the dog’s mouth or be given with food if necessary.
Instruction on how to divide the tablet: Put the tablet on an even surface, with its
scored side facing down (convex face up). With the tip of the forefinger, exert slight
vertical pressure on the middle of the tablet to break it along its width into halves.
Then, in order to obtain quarters, exert slight pressure on the middle of one half with
the forefinger to break it into two parts.
Do not use in case of hypersensitivity to the active substance or to any of the
excipients.
Do not use in cases of hypotension, hypovolaemia, hyponatraemia or acute renal
failure.
Do not use in cases of cardiac output failure due to aortic or pulmonary stenosis.
Do not use during pregnancy or lactation.
Dogs:
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Vomiting
Incoordination
Fatigue
Elevated creatinine
1
Transient
At the start of therapy. A moderate increase in plasma creatinine concentrations
following administration of ACE inhibitors is compatible with the reduction in
glomerular hypertension induced by these agents, and is therefore not necessarily a
reason to stop therapy in the absence of other signs.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
None.

Special precautions for safe use in the target species:
No evidence of renal toxicity of the veterinary medicinal product has been observed
during clinical trials, however, as is routine in cases of chronic kidney disease, it is
recommended to monitor plasma creatinine, urea and erythrocyte counts during
therapy.
The safety and efficacy of the product has not been examined in dogs weighing
less than 2.5 kg.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals

Angiotensin converting enzyme (ACE) inhibitors have been found to affect the unborn
child during pregnancy in humans. Pregnant women should take special care to
avoid accidental oral exposure.
Wash hands after use.
In case of accidental oral ingestion, seek medical advice immediately and show the
label or the package leaflet to the physician.
Special precautions for the protection of the environment:
Not applicable.
In dogs with congestive heart failure, this product has been given in combination with
digoxin, diuretics, pimobendan and anti-arrhythmic veterinary medicinal products
without demonstrable adverse interactions.
In humans, the combination of ACE inhibitors and Non-Steroidal Anti-Inflammatory
Drugs (NSAIDs) can lead to reduced anti-hypertensive efficacy or impaired renal
function. The combination of the product and other anti-hypertensive agents (e.g.
calcium channel blockers, ß-blockers or diuretics), anaesthetics or sedatives may
lead to additive hypotensive effects. Therefore, concurrent use of NSAIDs or other
medications with a hypotensive effect should be considered with care. Renal
function and signs of hypotension (lethargy, weakness etc) should be monitored
closely and treated as necessary.
Interactions with potassium preserving diuretics like spironolactone, triamterene or
amiloride cannot be ruled out. It is recommended to monitor plasma potassium levels
when using the product in combination with a potassium sparing diuretic because of
the risk of hyperkalaemia.
Do not store above 25
Store in the original package in order to protect from moisture.
Any part-used tablet should be returned to the opened blister and used within 72
hours.
Not applicable
4.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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