Milprazin 4 mg/10 mg Film-coated Tablets for Small Cats and Kittens Weighing at Least 0.5 kg
Active ingredients: Milbemycin Oxime (A3 and A4), Praziquantel
Form
Tablet
Species
Manufacturer
KRKA, d.d., Novo mesto
VMD MA No.
01656/5096
What it's used for
Treatment of mixed infections by immature and adult cestodes and nematodes of the following species: - Cestodes: Dipylidium caninum Taenia Echinococcus mul...
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Milprazin 4 mg/10 mg Film-coated Tablets for Small Cats and Kittens Weighing at Least 0.5 kg — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
following species:
- Cestodes:
Dipylidium caninum
Taenia
Echinococcus multilocularis
- Nematodes:
Ancylostoma tubaeforme
Toxocara cati
Revised: June 2024
AN: 02790/2023
Prevention of heartworm disease (Dirofilaria immitis) if concomitant treatment
against cestodes is indicated.
To ensure a correct dosage, body weight should be determined as accurately as
possible.
Revised: June 2024
AN: 02790/2023
Minimum recommended dose rate: 2 mg of milbemycin oxime and 5 mg of
praziquantel per kg are given orally as a single dose. The veterinary medicinal
product should be administered with or after some food. Doing so ensures optimum
protection against heartworm disease.
Depending on the bodyweight of the cat, the practical dosing is as follows:
Body weightFilm-coated tablets for small
cats and kittens
0.5 - 1 kg½ tablet > 1 - 2 kg1 tablet
The veterinary medicinal product can be inserted into a programme for prevention of
heartworm disease if at the same time treatment against tapeworms is indicated. For
the prevention of heartworm disease: the veterinary medicinal product kills Dirofilaria
immitis larvae up to one month after their transmission by mosquitoes. For regular
prevention of heartworm disease the use of a monosubstance is preferred.
Do not use in cases of hypersensitivity to the active substances or to any of the
excipients.
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Hypersensitivity reaction
Systemic disorders (e.g. lethargy)*
Neurological disorders (e.g. ataxia, muscle
tremor)*
Digestive tract disorders (e.g. emesis, diarrhoea)*
*Especially in young cats.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian,
to either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
contact details.
concomitantly.
In order to develop an effective worm control programme local epidemiological
information and the risk of exposure of the cat should be taken into account, and it is
recommended to seek professional advice.
When D. caninum infection is present, concomitant treatment against intermediate
hosts, such as fleas and lice, should be considered to prevent re-infection.
Parasite resistance to any particular class of anthelmintic may develop following
frequent, repeated use of an anthelmintic of that class.
Special precautions for use in animals
No studies have been performed with severely debilitated cats or individuals with
seriously compromised kidney or liver function. The veterinary medicinal product is
not recommended for such animals or only according to a benefit/risk assessment by
the responsible veterinarian.
Ensure cats and kittens weighing between 0.5 kg and ≤2 kg receive the appropriate
tablet strength (4 mg milbemycin oxime/10 mg praziquantel) and the appropriate
dose (1/2 or 1 tablet) for the corresponding weight band (1/2 tablet for cats weighing
0.5 to 1 kg; 1 tablet for cats weighing >1 to 2 kg).
As the tablets are flavoured, they should be stored in a safe place out of the reach of
animals.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
In case of accidental ingestion of the tablets, particularly by a child, seek medical
advice immediately and show the package leaflet or the label to the physician.
Wash hands after use.
Part tablets should be returned to the open blister and inserted into the outer carton.
Special precautions for the protection of the environment:
Not applicable.
Revised: June 2024
AN: 02790/2023
Other precautions
Echinococcosis represents a hazard for humans. As Echinococcosis is a notifiable
disease to the World Organisation for Animal Health (WOAH), specific guidelines on
the treatment and follow-up, and on the safeguard of persons, need to be obtained
from the relevant competent authority.
tolerated. No interactions were observed when the recommended dose of the
macrocyclic lactone selamectin was administered during treatment with milbemycin
oxime and praziquantel at the recommended dose. In the absence of further studies,
caution should be taken in the case of concurrent use of the veterinary medicinal
product and other macrocyclic lactones. Also, no such studies have been performed
with reproducing animals.
This veterinary medicinal product does not require any special temperature storage
conditions.
Halved tablets should be stored below 25°C in the original blister and be used for the
next administration.
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Related Conditions
Other Products Containing Milbemycin Oxime (A3 and A4)
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Aderexa 12.5 mg/125 mg Chewable Tablets for Dogs Weighing at Least 5 kg
POM-VKRKA, d.d., Novo mesto
Aderexa 2.5 mg/25 mg Chewable Tablets for Small Dogs and Puppies Weighing at Least 0.5 kg
POM-VKRKA, d.d., Novo mesto
Alpramil 12 mg/30 mg Film-coated Tablets for Cats Weighing at Least 3 kg
POM-VAlfasan Nederland B.V.
Alpramil 12 mg/30 mg Film-coated Tablets for Cats Weighing at Least 3 kg
POM-VAlfasan Nederland B.V.
Alpramil 12.5 mg/125 mg Tablets for Dogs Weighing at Least 5 kg
POM-VAlfasan Nederland B.V.
Alpramil 12.5 mg/125 mg Tablets for Dogs Weighing at Least 5 kg
POM-VAlfasan Nederland B.V.
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