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POM-V Prescription Required Companion Animal

Milbeworm 16 mg/40 mg Film-coated Tablets for Cats

Active ingredients: Milbemycin Oxime (A3 and A4), Praziquantel

Form

Tablet

Species

Cats

Manufacturer

Alfamed

VMD MA No.

17902/4081

What it's used for

In cats: treatment of mixed infections by immature and adult cestodes (tapeworms) and adult nematodes (roundworms) of the following species: Cestodes: Echi...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Clinical information

Milbeworm 16 mg/40 mg Film-coated Tablets for Cats — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

In cats: treatment of mixed infections by immature and adult cestodes (tapeworms)
and adult nematodes (roundworms) of the following species:
Cestodes:
Echinococcus multilocularis,
Dipylidium caninum,
Taenia spp.,
Nematodes:
Ancylostoma tubaeforme,
Toxocara cati
Prevention of heartworm disease (Dirofilaria immitis), if concomitant treatment
against cestodes is indicated.
Oral route.
As per good veterinary practice, animals should be weighed to ensure accurate
dosing.
Minimum recommended dose rate: 2 mg of milbemycin oxime and 5 mg of
praziquantel per kg are given once orally as a single dose.
The product should be administered with or after some food.
The product is a small size tablet.
To aid with administration, the product has been coated with a meat flavour.
The tablets can be divided into halves.

Revised: December 2021
AN: 01705/2021Page 4 of 7
Depending on the bodyweight of the cat, the practical dosing is as follows:
WeightTablets2 – 4 kg1/2 tablet>4 – 8 kg1 tablet>8 – 12 kg1½ tablets
In cases when heartworm disease prevention is used and at the same time treatment
against tapeworm is required, the product can replace the monovalent product for the
monthly prevention of heartworm disease.
Do not use in cats weighing less than 2 kg

Revised: December 2021
AN: 01705/2021Page 2 of 7
Do not use in cases of hypersensitivity to the active substances or to any of the
excipients.
In very rare occasions, especially in young cats, hypersensitivity reactions,
signs (such as lethargy), neurological signs (such as ataxia and muscle tremors)
and/or gastrointestinal signs (such as emesis and diarrhoea) may be observed after
administration of the veterinary medicinal product.
It is recommended to treat all the animals living in the same household
concomitantly.
Parasite resistance to any particular class of anthelmintic may develop following
frequent, repeated use of an anthelmintic of that class.
In order to develop an effective worm control programme local epidemiological
information and the living conditions of the cat should be taken into account and
therefore it is recommended to seek professional advice.
When D. caninum infection is present, concomitant treatment against intermediate
hosts, such as fleas and lice, should be considered to prevent re-infection.

Special precautions for use in animals
No studies have been performed with severely debilitated cats or individuals with
seriously compromised kidney or liver function. The product is not recommended for
such animals or only according to a benefit/risk assessment by the responsible
veterinarian.
Studies have shown that treatment of dogs with a high number of circulating
microfilariae can sometimes lead to the appearance of hypersensitivity reactions,
such as pale mucous membranes, vomiting, trembling, laboured breathing or
excessive salivation. These reactions are associated with the release of proteins
from dead or dying microfilariae and are not a direct toxic effect of the product. The
use in dogs suffering from microfilaremia is thus not recommended. In the absence
of data on cats with microfilaraemia, its use should be according to a benefit risk
assessment by the attending veterinarian.
As per good veterinary practice, animals should be weighed to ensure accurate
dosing.
Ensure cats and kittens weighing between 0.5 kg and ≤2 kg receive the appropriate
tablet strength (4 mg MBO/10 mg praziquantel) and the appropriate dose (1/2 or 1
tablet) for the corresponding weight band (1/2 tablet for cats weighing 0.5 to 1 kg ; 1
tablet for cats weighing >1 to 2 kg – 1 tablet).
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Wash hands after use.
In the event of accidental ingestion of the tablets, particularly by a child, seek medical
advice immediately and show the package leaflet or the label to the doctor.

Revised: December 2021
AN: 01705/2021Page 3 of 7
Other precautions
Echinococcosis represents a hazard for humans. As Echinococcosis is a notifiable
disease to the World Organisation for Animal Health (OIE), specific guidelines on the
treatment and follow-up, and on the safeguard of persons, need to be obtained from
the relevant competent authority (e. g. experts or institutes of parasitology) If the cat
has visited areas where spp. are prevalent, a veterinarian should be
consulted.
The concurrent use of the combination praziquantel/milbemycin oxime with
selamectin is well tolerated. No interactions were observed when the recommended
dose of the macrocyclic lactone selamectin was administered during treatment with
the combination at the recommended dose. In the absence of further studies, caution
should be taken in the case of concurrent use of the product and other macrocyclic
lactones.
This veterinary medicinal product does not require any special temperature storage
conditions.

Revised: December 2021
AN: 01705/2021Page 6 of 7
Half tablets should be stored in the original blister and be used for the next
administration.
Keep the blister in the outer carton.
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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