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POM-V Prescription Required Companion Animal

Milbactor 4 mg/10 mg Film-coated Tablets for Small Cats and Kittens Weighing at Least 0.5 kg

Active ingredients: Milbemycin Oxime (A3 and A4), Praziquantel

Form

Tablet

Species

Cats

Manufacturer

KRKA, d.d., Novo mesto

VMD MA No.

01656/4082

What it's used for

In cats: treatment of mixed infections by immature and adult cestodes and nematodes of the following species: - Cestodes: Dipylidium caninum Taenia Echinoc...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Prescription required

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Clinical information

Milbactor 4 mg/10 mg Film-coated Tablets for Small Cats and Kittens Weighing at Least 0.5 kg — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

In cats: treatment of mixed infections by immature and adult cestodes and
nematodes of the following species:
- Cestodes:
Dipylidium caninum
Taenia
Echinococcus multilocularis
- Nematodes:
Ancylostoma tubaeforme
Toxocara cati

Revised: July 2021
AN: 02341/2020 & 02342/2020Page 2 of 6
Prevention of heartworm disease (Dirofilaria immitis) if concomitant treatment against
cestodes is indicated.
Oral use.
Animals should be weighed to ensure accurate dosing.
Minimum recommended dose rate: 2 mg of milbemycin oxime and 5 mg of
praziquantel per kg are given orally as a single dose. The product should be
administered with or after some food. Doing so ensures optimum protection against
heartworm disease.
Depending on the bodyweight of the cat, the practical dosing is as follows:
WeightFilm-coated tablets for small
cats and kittens
0.5 - 1 kg½ tablet > 1 - 2 kg1 tablet
The product can be inserted into a programme for prevention of heartworm disease if
at the same time treatment against tapeworms is indicated. The product has a
duration of heartworm prevention of one month. For regular prevention of heartworm
disease the use of a monosubstance is preferred.

Revised: July 2021
AN: 02341/2020 & 02342/2020Page 4 of 6
Do not use in cats of less than 6 weeks of age and/or weighing less than 0.5 kg.
Do not use in known cases of hypersensitivity to the active substances or to any of
the excipients.
On very rare occasions, especially in young cats, systemic signs (such as lethargy),
neurological signs (such as ataxia and muscle tremors) and/or gastrointestinal signs
(such as emesis and diarrhoea) have been observed after administration of the
combination milbemycin/praziquantel.
On very rare occasions hypersensitivity reactions have been observed following
administration of the product.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
It is recommended to treat all the animals living in the same household
concomitantly.
In order to develop an effective worm control programme local epidemiological
information and the risk of exposure of the cat should be taken into account.
When D. caninum infection is present, concomitant treatment against intermediate
hosts, such as fleas and lice, should be considered to prevent re-infection.
Parasite resistance to any particular class of anthelmintic may develop following
frequent, repeated use of an anthelmintic of that class.

Special precautions for use in animals
No studies have been performed with severely debilitated cats or individuals with
seriously compromised kidney or liver function. The product is not recommended for
such animals or only according to a benefit/risk assessment by the responsible
veterinarian.
Ensure cats and kittens weighing between 0.5 kg and ≤2 kg receive the appropriate
tablet strength (4 mg milbemycin oxime/10 mg praziquantel) and the appropriate
dose (1/2 or 1 tablet) for the corresponding weight band (1/2 tablet for cats weighing
0.5 to 1 kg; 1 tablet for cats weighing >1 to 2 kg).
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
People with known hypersensitivity to the active substances or the excipients should
avoid contact with the veterinary medicinal product.
In the event of accidental ingestion of the tablets, particularly by a child, seek medical
advice immediately and show the package leaflet or the label to the doctor.
Wash hands after use.
Other precautions
Echinococcosis represents a hazard for humans. As Echinococcosis is a notifiable
disease to the World Organisation for Animal Health (OIE), specific guidelines on the
treatment and follow-up, and on the safeguard of persons, need to be obtained from
the relevant competent authority.

Revised: July 2021
AN: 02341/2020 & 02342/2020Page 3 of 6
The concurrent use of the milbemycin oxime and praziquantel with selamectin is well
tolerated. No interactions were observed when the recommended dose of the
macrocyclic lactone selamectin was administered during treatment with milbemycin
oxime and praziquantel at the recommended dose. In the absence of further studies,
caution should be taken in the case of concurrent use of the product and other
macrocyclic lactones. Also, no such studies have been performed with reproducing
animals.
Store in the original package in order to protect from moisture.
This veterinary medicinal product does not require any special temperature storage
conditions.
Halved tablets should be stored below 25°C in the original blister and be used for the
next administration.
Keep the blister in the outer carton.
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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