POM-V Prescription Required

Hyonate 10 mg/ml Solution for Injection

Active ingredient: Sodium Hyaluronate

Form

Injection

Species

Horses

Manufacturer

Boehringer Ingelheim Animal Health UK Limited

VMD MA No.

08327/5055

What it's used for

For adjunctive intra-articular treatment of joint disease associated with non-infectious synovitis in horses.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Sodium Hyaluronate

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Hyonate 10 mg/ml Solution for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For adjunctive intra-articular treatment of joint disease associated with non-infectious
synovitis in horses.

For single intra-articular injection: 2.5 ml intra-articularly into medium sized and large
joints. More than one joint may be treated at the same time.

Revised: December 2025
MA split from NI Expiry following AN: 02055/2025
A sterile dressing and clean bandage should be applied after injection, as appropriate for
the particular joint treated.
If necessary, re-treatment of the joint can be considered at 2-3 weeks after the first-
treatment.
Single dose syringes made ready for injection shall be used immediately; any
unused portion of a syringe is to be discarded.

Do not use in cases of joint infections.
Do not use in case of known hypersensitivity to exogenous sodium hyaluronate or to any
of the excipients of the product.

The most commonly reported adverse reaction are transient mild swelling and/or heat
occurring in approximately 2.7% of the treated joints. These self-limiting local signs
typically resolve spontaneously within 48 hours. However, since the early signs of septic
arthritis may be similar, it is advised that a thorough clinical examination and monitoring
are carried out if these clinical signs occur. Consideration should be given to appropriate
further investigations.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

The treated horse should be box-rested for 2 days before gradually resuming a
normal exercise pattern.

Revised: December 2025
MA split from NI Expiry following AN: 02055/2025

i) Special precautions for use in animals
Excess synovial fluid should be removed whenever possible prior to injection.
The injection should be administered under strict aseptic conditions through
healthy undamaged skin.
Appropriate investigations should be carried out in cases of acute, severe lameness
to ensure that the joints are free from fractures, OCD fragments and infections.
ii) Special precautions to be taken by the person administering the
veterinary

medicinal product to animals
In case of accidental contact with skin, wash with soap and water.
In case of accidental contact with eyes, blurred vision may occur because of the viscous
nature of the product. Rinse immediately with plenty of clean water.
In the event of accidental self-injection, seek medical advice immediately and show
the package leaflet of the label to the physician.
Wash hands after use.

No data available regarding the interaction with other medicinal products. It is described
that hyaluronic acid competes with other high molecular weight polysaccharides such as
chondroitin sulphate for receptor binding and thus for uptake in the articular cartilage
tissue.

Do not store above 25°C Store in the original container Store in a dry place

Meat and offal: zero days Milk: zero hours
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.