Fortekor Plus 5mg/10mg Tablets
Active ingredients: Benazepril Hydrochloride, Pimobendan
Form
Tablet
Species
Manufacturer
Elanco GmbH
VMD MA No.
52127/5015
What it's used for
and should only be used in patients whose clinical signs are successfully controlled by administration of the same doses of the individual components (pimo...
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Fortekor Plus 5mg/10mg Tablets — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
administration of the same doses of the individual components (pimobendan and benazepril
hydrochloride) given concurrently.
This veterinary medicinal product is a fixed combination product which should only be used in
dogs which require both active substances to be administered concomitantly at this fixed dose.
The recommended dose range for this veterinary medicinal product is 0.25–0.5 mg
pimobendan per kg body weight and 0.5–1 mg benazepril hydrochloride per kg body weight
divided into two daily doses. This veterinary medicinal product should be administered orally,
twice daily 12 hours apart (morning and evening) and approximately 1 hour before feeding.
The tablets are breakable along the score line.
AN: 02229/2024Page 5 of 8
The table below may be used for guidance.
Strength and number of tablets to be administeredFORTEKOR PLUS 5 mg/10 mg tablets
Body weight
(kg) of dog
MorningEvening10 – 200.50.520 – 4011Over 40 kg22
augmentation of cardiac output is not possible for functional or anatomical reasons (e.g. aortic
or pulmonary stenosis).
Do not use in cases of hypotension, hypovolaemia, hyponatremia or acute renal failure.
Do not use during pregnancy and lactation (see section 3.7).
Do not use in cases of hypersensitivity to the active substances or to any of the excipients.
Rare
(1 to 10 animals / 10,000 animals treated):
Increased heart rate
Diarrhoea
, Vomiting
1,2
Anorexia
, Lethargy
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Elevated creatinine
Incoordination
Fatigue
1
Moderaate. These effects are dose-dependent and can be avoided by reducing the dose in
those cases.
Transient.
At the start of therapy in dogs with chronic kidney disease. A moderate increase in plasma
creatinine concentrations following administration of ACE inhibitors is compatible with the
reduction in glomerular hypertension induced by these agents, and is therefore not necessarily
a reason to stop therapy in the absence of other signs.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary
medicinal product. Reports should be sent, preferably via a veterinarian, to either the
marketing authorisation holder or the national competent authority via the national reporting
system. See the package leaflet for respective contact details.
Special precautions for safe use in the target species:
In cases of chronic kidney disease, it is recommended to check the dog’s hydration status
before starting therapy, and to monitor its plasma creatinine and blood erythrocyte counts
during therapy.
As pimobendan is metabolised in the liver, the veterinary medicinal product should not be
administered to dogs with severe hepatic insufficiency.
The efficacy and safety of the veterinary medicinal product has not been established in dogs
below 2.5 kg body weight or under 4 months of age.
Special precautions to be taken by the person administering the veterinary medicinal product
to animals
Wash hands after use.
AN: 02229/2024Page 3 of 8
People with known hypersensitivity to pimobendan or benazepril hydrochloride should avoid
contact with the veterinary medicinal product.
In case of accidental ingestion, seek medical advice immediately and show the package leaflet
or the label to the physician.
Pregnant women should take special care to avoid accidental oral exposure because
angiotensin converting enzyme (ACE) inhibitors have been found to affect the unborn child
during pregnancy in humans.
Special precautions for the protection of the environment:
Not applicable.
given in combination with digoxin and diuretics without demonstrable adverse interactions.
In pharmacological studies no interaction between the cardiac glycoside ouabain and
pimobendan was detected. The pimobendan-induced increase in contractility of the heart is
attenuated in the presence of the calcium antagonist verapamil and the ß-antagonist
propranolol.
In man, the combination of angiotensin converting enzyme (ACE) inhibitors and non-steroidal
anti- inflammatory drugs (NSAIDs) can lead to reduced anti-hypertensive efficacy or impaired
renal function. Therefore, the concurrent use of the veterinary medicinal product with NSAIDs
or any other medications with a hypotensive effect should be considered carefully before using
such combinations.
The combination of the veterinary medicinal product and other anti-hypertensive agents (e.g.
calcium channel blockers,
additive hypotensive effects. Renal function and signs of hypotension (lethargy, weakness,
etc) should be monitored closely and treated as necessary.
Interactions with potassium-sparing diuretics such as spironolactone, triamterene or amiloride
cannot be ruled out. It is therefore recommended to monitor plasma potassium levels when
using the veterinary medicinal product in combination with a potassium sparing diuretic
because of the risk of hyperkalemia.
Keep the blister in the outer carton in order to protect from moisture.
Any remaining half tablet should be placed back in the opened blister and stored (for a
maximum of 1 day) in the original cardboard carton.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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