Fatrobendan 5 mg, Chewable Tablets for Dogs
Active ingredient: Pimobendan
Form
Tablet
Species
Manufacturer
Fatro S.p.A.
VMD MA No.
11557/3004
What it's used for
For the treatment of dilated cardiomyopathy in the preclinical stage (asymptomatic with an increase in left ventricular end-systolic and end-diastolic diam...
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1
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Fatrobendan 5 mg, Chewable Tablets for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
with an increase in left ventricular end-systolic and end-diastolic diameter) in
Doberman Pinschers following echocardiographic diagnosis of cardiac disease.
To ensure a correct dosage, the bodyweight should be determined as accurately as
possible.
A dosage range of 0.2 mg to 0.6 mg pimobendan/kg bodyweight, divided into two
daily doses, should be respected. The preferrable daily dose is 0.5 mg
pimobendan/kg bodyweight divided into two daily doses given approximately
12 hours apart (i.e., 0.25 mg pimobendan/kg bodyweight equivalent to 0.17 ml of the
veterinary medicinal product twice daily).
The solution should be given using the measuring syringe provided in the package.
The syringe has a kg bodyweight scale with 0.5 kg increments up to a bodyweight of
12 kg and fits onto the bottle. Each 1 kg increment corresponds to 0.25 mg
pimonbendan. The total bodyweight of the animal should be used for each
administration. For example, for a 6 kg dog, the veterinary medicinal product should
be drawn up to the 6 kg mark on the syringe for each administration (this equates to
a 0.25 mg pimobendan/kg bodyweight dose per administration). Do not exceed the
recommended dosage.
Each dose should be given directly into the mouth on an empty stomach,
approximately one hour before feeding. After administration, close the bottle tightly
using the cap. Clean the outside of the syringe by wiping with a clean, dry cloth or
tissue after each use. The contaminated tissue should be immediately disposed of.
If the syringe clogs, rinse without removing the plunger by using water and wiping the
outside of the syringe dry with a clean cloth or tissue. To avoid contamination, use
the provided syringe only to administer this oral solution. The used syringe should be
stored with the veterinary medicinal product in the original carton.
Pimobendan may also be used in combination with a diuretic e.g., furosemide.
Advice on correct administration
The veterinary medicinal product consists of a bottle
sealed with a child-resistant cap A, a second child-resistant
cap with integrated plug-in adapter B and a measuring
dosing syringe with a kg-bodyweight scale C.
Do not shake the bottle prior to use (this avoids foaming).
Open the bottle in an upright position by pressing down on
the child-resistant cap A and simultaneously turning the
cap anticlockwise. Discard the white cap A.
Tightly close the bottle using the cap B and turn
simultaneously the cap clockwise. The cap B contains an
integrated plug-in adapter which should automatically
attach to the bottle A. Ensure the cap is tightly closed to
appropriately insert plug.
Remove the cap B from the bottle by pressing down on the
child-resistant cap and simultaneously turning the cap
anticlockwise and gently push the end of the dosing
syringe
Turn the bottle and syringe upside down.
Pull the plunger out and fill the dosing syringe to the dose
prescribed by your veterinarian.
Turn the bottle upright and remove the dosing syringe from
the bottle Close the bottle with cap B.
Put the end of the doing syringe C into your dog´s mouth
and push the plunger to give the prescribed dose.
an improvement in cardiac output cannot be achieved for functional or anatomical
reasons (e.g. aortic stenosis).
Since pimobendan is metabolised mainly via the liver, it should not be used in
dogs with severe impairment of liver function (see also section 3.7).
Rare
(1 to 10 animals / 10,000
animals treated):
Increased heart rate
a,b
;
Vomiting
b
, Diarrhoea
c
;
Anorexia
c
, Lethargy
c
;
Heart valve disorder
d
.
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Mucosa petechiae
e
, Skin (subcutaneous)
haemorrhage
e.
a
slight positively chronotropic effect.
b
these effects are dose-dependent and can be avoided by reducing the dose.
c
transient.
d
an increase in mitral valve regurgitation has been observed during chronic
pimobendan treatment in dogs with mitral valve disease.
e
these signs of effects on primary haemostasis disappear when the treatment is
withdrawn.
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or its local
representative or the national competent authority via the national reporting
system. See package leaflet for respective contact details.
Special precautions for safe use in the target species:
Monitoring of cardiac function and morphology is recommended in animals
treated with pimobendan (see also section 3.6).
Use with caution in epileptic dogs.
The tablets are flavoured. In order to avoid any accidental ingestion, store tablets
out of reach of the animals.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals:
People with known hypersensitivity to pimobendan or to any of the excipients
should avoid contact with the veterinary medicinal product.
To avoid accidental ingestion, especially by a child, unused tablet parts should
be placed back into the blister and carton and carefully kept from children. Part
used tablets should be used at the time of the next dose.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
Wash hands after use.
Advice to doctors: accidental ingestion, especially by a child, may lead to the
occurrence of tachycardia, orthostatic hypotension, flushing of the face and
headaches.
Special precautions for the protection of the environment:
Not applicable.
strophanthin and pimobendan was observed.
The pimobendan-induced increase in cardiac contractility is attenuated by the
calcium antagonists verapamil and diltiazem and by the
conditions.
Monitoring of cardiac function and morphology is recommended in animals
treated with pimobendan (see also section 3.6).
Use with caution in epileptic dogs.
The tablets are flavoured. In order to avoid any accidental ingestion, store tablets
out of reach of the animals.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals:
People with known hypersensitivity to pimobendan or to any of the excipients
should avoid contact with the veterinary medicinal product.
To avoid accidental ingestion, especially by a child, unused tablet parts should
be placed back into the blister and carton and carefully kept from children. Part
used tablets should be used at the time of the next dose.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
Wash hands after use.
Advice to doctors: accidental ingestion, especially by a child, may lead to the
occurrence of tachycardia, orthostatic hypotension, flushing of the face and
headaches.
Special precautions for the protection of the environment:
Not applicable.
3.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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