Endogard Plus XL Tablets for Dogs
Active ingredients: Febantel, Praziquantel, Pyrantel Embonate
Form
Tablet
Species
Manufacturer
KRKA, d.d., Novo mesto
VMD MA No.
01656/4018
What it's used for
Treatment of flea infestation in dogs (Ctenocephalides felis and C. canis). One treatment provides immediate and persistent flea killing activity for 5 wee...
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1
Ask your vet for a written prescription
They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
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2
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Endogard Plus XL Tablets for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
treatment provides immediate and persistent flea killing activity for 5 weeks. The
product can be used as part of a treatment strategy for the control of flea allergy
dermatitis (FAD) where this has been previously diagnosed by a veterinarian.
Treatment of tick infestation in dogs (Dermacentor reticulatus, Ixodes ricinus,
Rhipicephalus sanguineus). One treatment provides immediate and persistent tick
killing activity for one month.
Fleas and ticks must attach to the host and commence feeding in order to be
exposed to the active substance.
The recommended dose rates are: 15 mg/kg bodyweight febantel, 14.4 mg/kg
pyrantel and 5 mg/kg praziquantel. This is equivalent to 1 tablet per 35 kg
bodyweight.
Tablets may be halved to allow accuracy of dosing.
Administration and Duration of Treatment
No restriction of access to food is required either before or after administration of the
veterinary medicinal product. The tablet(s) can be given directly to the dog or
disguised in food.
To a correct dosage, bodyweight should be determined as accurately as possible.
For the control of , nursing bitches should be dosed 2 weeks after giving
birth and every 2 weeks until weaning.
In the event of a heavy roundworm infestation, a repeat dose should be given after
14 days.
For routine control adult dogs should be treated every 3 months.
Do not use in cases of hypersensitivity to the active substance or to any of
excipients.
Do not exceed the stated dosage when treating pregnant bitches.
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Vomiting, diarrhoea
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
AN: 00022/2024 & AN: 00027/2024
competent authority via the national reporting system. See also the package leaflet
for contact details.
caninum. Tapeworm infestation is certain to re-occur unless control of intermediate
hosts such as fleas, mice etc. is undertaken.
Special precautions for safe use in the target species:
This veterinary medicinal product is not recommended for use in dogs under 17.5 kg
body weight.
Any part-used tablets should be discarded.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
In the interests of good hygiene, persons administering the tablet directly to a dog or
by adding it to the dog's food, should wash their hands afterwards.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or label to the physician.
Special precautions for the protection of the environment:
Not applicable.
piperazine (used in many worming veterinary medicinal products for dogs) may be
antagonized.
Concurrent use with other cholinergic compounds can lead to toxicity.
4.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Related Conditions
Other Products Containing Febantel
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Anthelmin Plus Flavour Tablets for Dogs
NFA-VPSKRKA, d.d., Novo mesto
Anthelmin Plus XL Tablets for Dogs
NFA-VPSKRKA, d.d., Novo mesto
Avicas, Febantel 15 mg, Tablet
AVM-GSLOropharma n.v
Beaphar WORMclear Tablets for Dogs
AVM-GSLC&H Generics Ltd
Bob Martin Clear 3 in 1 Flavoured Wormer 150/144/50 mg Tablets for Dogs
AVM-GSLVetoquinol UK Limited
Bob Martin Clear 3 in 1 Flavoured Wormer XL 525/504/175 mg Tablets for Large Dogs
AVM-GSLVetoquinol UK Limited
Alternative options to consider
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Wormers for Dogs
Drontal, Milbemax, Panacur and generic wormers for dogs. Dispensed by a UK registered pharmacy.
Pet Wormers at Pharmacy2U
Drontal, Milbemax and own-brand wormers dispensed by the UK's largest online pharmacy.
VetBox Flea & Worm Protection for Dogs
Vet-founded monthly parasite subscription. Flea, tick and worm protection delivered to your door. Founded by Dr Will Woodley, protecting 30,000+ pets.
We may earn a small commission if you purchase through these links, at no extra cost to you.
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