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NFA-VPS Over the Counter Companion Animal

Endogard Plus Flavour Tablets for Dogs

Active ingredients: Febantel, Praziquantel, Pyrantel Embonate

Form

Tablet

Species

Dogs

Manufacturer

KRKA, d.d., Novo mesto

VMD MA No.

01656/4017

What it's used for

Do not use simultaneously with piperazine compounds. Do not exceed the stated dosage when treating pregnant bitches. Do not use in in cases of hypersensiti...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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  1. 1

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  2. 2

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Clinical information

Endogard Plus Flavour Tablets for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Do not use simultaneously with piperazine compounds.
Do not exceed the stated dosage when treating pregnant bitches.
Do not use in in cases of hypersensitivity to the active substances or to any of the
excipients.
Do not use in dogs younger than 2 weeks of age and/or weighing less than 2 kg.
3.4 Special warnings
Fleas serve as intermediate hosts for one common type of tapeworm – Dipylidium
caninum. Tapeworm infestation is certain to re-occur unless control of intermediate
hosts such as fleas, mice etc. is undertaken.
3.5 Special precautions for use
Special precautions for safe use in the target species:
Any part-used tablets should be discarded.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
In the interests of good hygiene, persons administering the tablet directly to a dog or
by adding it to the dog's food should wash their hands afterwards.
In case of accidental ingestion, seek medical advice and show the package leaflet to
the physician.
Special precautions for the protection of the environment:
Not applicable.
3.6 Adverse events
Dogs:
Rare
(1 to 10 animals / 10,000
animals treated):
Loose stool
, diarrhoea
1,2
, vomiting
1,2
In puppies: transient.
In adult dogs: very rare cases of vomiting, with or without diarrhoea.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
contact details.
AN: 00022/2024 & AN: 00027/2024
3.7 Use during pregnancy, lactation or lay
Consult a veterinary surgeon before treating pregnant animals for roundworms.
The product may be used during lactation (see Sections
Dosage
The recommended dose rates are: 15 mg/kg bodyweight febantel, 14.4 mg/kg
pyrantel and 5 mg/kg praziquantel. This is equivalent to 1 tablet per 10 kg
bodyweight.
Tablets may be halved/quartered to allow accuracy of dosing.
Administration and Duration of Treatment
The tablet(s) can be given directly to the dog or disguised in food. No restriction of
access to food is required either before or after administration of the product.
To ensure a correct dosage, body weight should be determined as accurately as
possible.
Puppies may be wormed with this product from 2 weeks of age and every 2 weeks
until 12 weeks of age. Thereafter they should be treated at 3 monthly intervals. It is
advisable to treat the bitch at the same time as the puppies.
For the control of Toxocara, nursing bitches should be dosed 2 weeks after giving
birth and every 2 weeks until weaning.
For routine control a single dose is recommended at 3 monthly intervals.
In the event of a heavy roundworm infestation, a repeat dose should be given after
14 days.
Do not use simultaneously with piperazine compounds.
Do not exceed the stated dosage when treating pregnant bitches.
Do not use in in cases of hypersensitivity to the active substances or to any of the
excipients.
Do not use in dogs younger than 2 weeks of age and/or weighing less than 2 kg.
Dogs:
Rare
(1 to 10 animals / 10,000
animals treated):
Loose stool
, diarrhoea
1,2
, vomiting
1,2
In puppies: transient.
In adult dogs: very rare cases of vomiting, with or without diarrhoea.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
contact details.
AN: 00022/2024 & AN: 00027/2024
Fleas serve as intermediate hosts for one common type of tapeworm – Dipylidium
caninum. Tapeworm infestation is certain to re-occur unless control of intermediate
hosts such as fleas, mice etc. is undertaken.

Special precautions for safe use in the target species:
Any part-used tablets should be discarded.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
In the interests of good hygiene, persons administering the tablet directly to a dog or
by adding it to the dog's food should wash their hands afterwards.
In case of accidental ingestion, seek medical advice and show the package leaflet to
the physician.
Special precautions for the protection of the environment:
Not applicable.
Do not use simultaneously with piperazine as the anthelmintic effects of pyrantel and
piperazine (used in many worming products for dogs) may be antagonized.
Concurrent use with other cholinergic compounds can lead to toxicity.
This veterinary medicinal product does not require any special storage conditions.
Not applicable.
AN: 00022/2024 & AN: 00027/2024

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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