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POM-V Prescription Required Companion Animal

Elanco Milbemycin - Praziquantel 4 mg/10 mg Film-Coated Tablets for Small Cats and Kittens

Active ingredients: Milbemycin Oxime (A3 and A4), Praziquantel

Form

Tablet

Species

Cats

Manufacturer

Elanco Europe Ltd

VMD MA No.

00879/5008

What it's used for

In cats: treatment of mixed infections by immature and adult cestodes and nematodes of the following species: - Dipylidium caninum Taenia spp. Echinococcus...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Clinical information

Elanco Milbemycin - Praziquantel 4 mg/10 mg Film-Coated Tablets for Small Cats and Kittens — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 18 Mar 2026.

In cats: treatment of mixed infections by immature and adult cestodes and nematodes
of the following species:
-
Dipylidium caninum
Taenia spp.
Echinococcus multilocularis
-
Ancylostoma tubaeforme
Toxocara cati
Prevention of heartworm disease (Dirofilaria immitis) if concomitant treatment against
cestodes is indicated.
Minimum recommended dose rate: 2 mg of milbemycin oxime and 5 mg of praziquantel
per kg are given orally as a single dose. The product should be administered with or
after some food. Doing so ensures optimum protection against heartworm disease.
Depending on the bodyweight of the cat, the practical dosing is as follows:
WeightTablets 0.5 - 1 kg½ tablet > 1 - 2 kg1 tablet
Elanco Milbemycin - Praziquantel 4 mg/10 mg film-coated tablets for small cats and
kittens can be inserted into a programme for prevention of heartworm disease if at the
same time treatment against tapeworms is indicated. Elanco Milbemycin - Praziquantel
4 mg/10 mg film-coated tablets for small cats and kittens has a duration of heartworm
prevention of one month. For prevention of heartworm disease the use of a
monosubstance is preferred.
Do not use in cats of less than 6 weeks of age and/or weighing less than 0.5 kg.

Issued December 2022
AN: 00877/2022
In very rare occasions, especially in young cats, hypersensitivity reactions, systemic
signs (such as lethargy), neurological signs (such as ataxia and muscle tremors) and/or
gastrointestinal signs (such as emesis and diarrhoea) have been observed after
administration of the veterinary medicinal product.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

Issued December 2022
AN: 00877/2022
In order to develop an effective worm control programme local epidemiological
information and the risk of exposure of the cat should be taken into account.
It is recommended to treat all the animals living in the same household concomitantly.
When infection with the cestode D. caninum has been confirmed, concomitant
treatment against intermediate hosts, such as fleas and lice, should be discussed with a
veterinarian to prevent re-infection.

Special precautions for use in animals
As per good veterinary practice, animals should be weighed to ensure accurate dosing.
Ensure cats and kittens weighing between 0.5 kg and ≤2 kg receive the appropriate
tablet strength (4 mg MBO/10 mg praziquantel) and the appropriate dose (1/2 or 1
tablet) for the corresponding weight band (1/2 tablet for cats weighing 0.5 to 1 kg ; 1
tablet for cats weighing >1 to 2 kg – 1 tablet).
Echinococcosis represents a hazard for humans. In case of Echinococcosis, specific
guidelines on the treatment and follow up and on the safeguard of persons have to be
followed. Experts or institutes of parasitology should be consulted.
No studies have been performed with severely debilitated cats or individuals with
seriously compromised kidney or liver function. The product is not recommended for
such animals or only according to a benefit/risk assessment by the responsible
veterinarian.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Wash hands after use.
In the event of accidental ingestion of the tablets, particularly by a child, seek medical
advice immediately and show the package leaflet or the label to the physician.
The concurrent use of Elanco Milbemycin - Praziquantel 4 mg/10 mg film-coated tablets
for small cats and kittens with selamectin is well tolerated. No interactions were
observed when the recommended dose of the macrocyclic lactone selamectin was
administered during treatment with Elanco Milbemycin - Praziquantel 4 mg/10 mg film-
coated tablets for small cats and kittens at the recommended dose.
Although not recommended, the concomitant use of Elanco Milbemycin - Praziquantel 4
mg/10 mg film-coated tablets for small cats and kittens with a spot on containing
moxidectin and imidacloprid at recommended dose rates following a single application
was well tolerated in one laboratory study in 10 kittens.
The safety and efficacy of the concurrent use have not been investigated in field
studies. In the absence of further studies, caution should be taken in the case of
concurrent use of the product with any other macrocyclic lactone. Also, no such studies
have been performed with reproducing animals.
Do not store above 25 °C
Keep the blister in the outer carton in order to protect from light
Not applicable.

Issued December 2022
AN: 00877/2022
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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