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AVM-GSL Over the Counter Companion Animal

Drontal Oral Suspension for Puppies Febantel 15 mg/ml / Pyrantel 5 mg/ml

Active ingredients: Febantel, Pyrantel

Form

Liquid

Species

Dogs

Manufacturer

Vetoquinol UK Limited

VMD MA No.

08007/5002

What it's used for

Treatment of flea infestation in dogs (Ctenocephalides felis and C. canis). One treatment provides immediate and persistent flea killing activity for 5 wee...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Febantel + Pyrantel

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Clinical information

Drontal Oral Suspension for Puppies Febantel 15 mg/ml / Pyrantel 5 mg/ml — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Treatment of flea infestation in dogs (Ctenocephalides felis and C. canis). One
treatment provides immediate and persistent flea killing activity for 5 weeks. The
product can be used as part of a treatment strategy for the control of flea allergy
dermatitis (FAD) where this has been previously diagnosed by a veterinarian.
Treatment of tick infestation in dogs (Dermacentor reticulatus, Ixodes ricinus,
Rhipicephalus sanguineus). One treatment provides immediate and persistent tick
killing activity for one month.
Fleas and ticks must attach to the host and commence feeding in order to be
exposed to the active substance.
Underdosing could result in ineffective use and may favour resistance development
To ensure administration of the correct dose, body weight should be determined as
accurately as possible.
Ascarid roundworm infestation may occur in dogs at a very young age due to infection
whilst within the womb, or via the mother’s milk. For some animals, especially in case
of severe infections, elimination of ascarids may be incomplete, and a potential risk of
infections to humans cannot be excluded. Where epidemiologically appropriate, it is
recommended that treatment should be started at 2 weeks of age and should be
performed repeatedly at suitable intervals (for example every 2 weeks), until weaning.
Otherwise treatment should be based upon confirmed infection, for example the
results of faecal examinations.
The need for and frequency of re-treatment(s) should be based on professional advice
(from a veterinarian or suitably qualified professional) and should take into account the
local epidemiological situation and the animal’s lifestyle.
Method of Administration
Single Oral administration.
The product may be given directly to the animal or mixed with feed using the syringe
supplied with the pack. No special dietary measures are necessary; access to normal
diet does not need to be limited before or after treatment.
1. Measure the animal’s bodyweight accurately to ensure correct dosage.
2. Mix the product by gently turning the container upside down and then back upright
a few times.
3. Remove the bottle cap and place the tip of the syringe provided into the neck of
the bottle. Turn the bottle upside down and then pull the syringe plunger out
allowing the liquid to flow into the syringe chamber. Continue pulling the plunger
out until the liquid reaches the desired dosage line (1ml suspension per kilogram
of bodyweight).
4. Turn the bottle upright and carefully separate the syringe from the bottle.
5. Replace the bottle top.
6. The measured amount of product may then be given to the animal. To do this,
push the plunger to empty the full contents of the syringe directly into the corner of
the mouth of the animal, or mix with food and ensure the full dose is ingested.
Do not use simultaneously with compounds containing piperazine as piperazine may
block the action of pyrantel embonate contained in the product. Other worming products
may contain piperazine.
Do not use simultaneously with other worming products without veterinary advice.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Do not use during pregnancy
Do not use in lactating bitches
(<1 animal / 10,000 animals treated,
including isolated reports):
Digestive tract disorder
(diarrhoea
,
vomiting
)
Mild and transient.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
Care should be taken to administer the product according to the package leaflet and
avoid unnecessary use of worming treatments, as this may increase the risk of
development of resistance and could ultimately result in ineffective therapy. Advice from
a veterinary or suitably qualified professional should be sought to identify the presence
or risk of worm infection based on the animal’s individual lifestyle.
Dogs may become re-infected with roundworms following treatment. Ongoing exposure
to worms can occur from eggs in the environment, or by eating birds, small rodents or
rabbits, or scavenging livestock carcasses. The need for and interval between
treatments will vary depending on the dogs environment and lifestyle. For guidance
specific to your dog, consult your vet or suitably qualified professional. Treating your
dog will reduce the risk of other animals and humans being exposed.

Special precautions for safe use in the target species:
The safety of the product has not been assessed in puppies younger than 2 weeks and
weighing less than 0.6 kg.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Wash hands after use,
The product may cause skin or eye irritation.
Avoid direct contact with the skin and eyes. In case of accidental spillage wash the
affected area immediately with clean running water.
Special precautions for the protection of the environment:
Not applicable.
The anthelmintic effects of both pyrantel (spastic paralysis) and piperazine
(neuromuscular paralysis) may be antagonised when the two drugs are used together.
Other worming products may contain piperazine. Do not use simultaneously with other
deworming products without veterinary advice
This unopened veterinary medicinal product does not require any special storage
conditions.
After opening, store the product at a temperature not exceeding 25 ºC.
Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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