Dexacortone 0.5 mg Chewable Tablets for Dogs and Cats

Corticoid administration is to induce an improvement in clinical signs rather than
a cure. The treatment should be combined with treatment of the underlying
disease and/or environmental control.

Special precautions for use in animals
In cases where it has been deemed necessary to administer the veterinary
medicinal product in the presence of bacterial, parasitic or fungal infection, the
underlying infection should be treated concomitantly with suitable antibacterial,
antiparasitic or antifungal therapy.
Because of the pharmacological properties of dexamethasone, special care
should be taken when the veterinary medicinal product is used in animals with a
weakened immune system.
Corticoids such as dexamethasone, exacerbate proteinaceous catabolism.
Consequently, the veterinary medicinal product should be used with caution in
old or malnourished animals.
Corticoids such as dexamethasone should be used with caution in patients with
hypertension.
Since glucocorticosteroids are known to slow growth, use in young animals
(under 7 months of age) should be based on a benefit/risk assessment by the
attending veterinarian.
Pharmacologically-active dose levels may lead to atrophy of the adrenal cortex,
resulting in adrenal insufficiency. This may become apparent particularly after
withdrawal of corticosteroid treatment. The dosage should be reduced and
withdrawn gradually to avoid precipitation of adrenal insufficiency.
Avoid long-term use with oral corticosteroids whenever possible. Should long-
term use be indicated, a corticosteroid with a shorter duration of action e.g.
prednisolone is more appropriate. With prednisolone, alternate-day therapy can
be utilised for longer-term use to minimise adrenal insufficiency. Due to the long
duration of effect of dexamethasone alternate day therapy is not an adequate
way to allow the hypothalamic-pituitary-adrenal axis to recover (see section
4.9).
The tablets are flavoured. In order to avoid any accidental ingestion, store
tablets out of reach of animals.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Dexamethasone may cause hypersensitivity (allergic) reactions. Skin contact
with the veterinary medicinal product should be avoided, especially in people
with known hypersensitivity to dexamethasone or any of the excipients (e.g.
povidone or lactose). Wash hands after use. Seek medical advice in case of
hypersensitivity reactions.
This veterinary medicinal product may be harmful to children after accidental
ingestion. Do not leave the veterinary medicinal product unattended. Return

Revised: August 2025
AN: 01855/2023Page 3 of 7
unused part-tablets to the blister pack and use them on the next administration.
Keep the blister in the outer carton to prevent access by children. In case of
accidental ingestion, seek medical advice immediately and show the package
leaflet or the label to the physician.
Dexamethasone can cause harm to unborn children. Pregnant women should
avoid exposure. Absorption through the skin is negligible but it is recommended
to immediately wash hands after handling the tablets to avoid hand-to-mouth
contact.
Special precautions for the protection of the environment
Not applicable.
Other precautions
Not applicable.