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POM-V Prescription Required Companion Animal

Daxocox 100 mg Tablets for Dogs

Active ingredient: Enflicoxib

Form

Tablet

Species

Dogs

Manufacturer

Ecuphar NV

VMD MA No.

EU/2/21/270/029-035

What it's used for

For the treatment of pain and inflammation associated with orthopaedic or soft tissue surgery.

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Enflicoxib

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Daxocox 100 mg Tablets for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For the treatment of pain and inflammation associated with orthopaedic or soft tissue
surgery.
Dosing interval is ONCE PER WEEK.
Osteoarthritis:
First dose: 8 mg enflicoxib per kg body weight.
Maintenance dose: repeat the treatment every 7 days at the dose of 4 mg enflicoxib
per kg body weight.
Number of tablets to be administered FIRST DOSEMAINTENANCE DOSE 8 mg/kg4 mg/kgBody
weight
(Kg)
/Tablet
size (mg)
m
g
m
g
m
g
m
g
0
mg
0
mg
0
mg
m
g
m
g
m
g
m
g
0
mg
0
mg
0
mg
2.5 - 4.92 1 5 - 7.5 2 1 7.6 – 11.2 2 1
11.3 -
17.5
2 1
17.6 - 25 2 1 25.1 - 35 2 1 35.1 - 50 2 150.1 - 75 4 2
For perioperative use:
A single treatment at a dose of 8 mg per kg body weight must be administered one
day (at least 24 hours) before surgery is scheduled. If, at 7 days after the initial
treatment (6 days post-surgery), the treating veterinarian determines that further
post-operative analgesia is necessary, subsequent treatments may be administered
at a dose of 4 mg per kg body weight and at a 7-day treatment interval.
The veterinary medicinal product should be given immediately before or with the
dog’s meal.
To ensure a correct dosage, body weight should be determined as accurately as
possible.
Do not use in animals suffering from gastrointestinal disorders, protein or blood
losing enteropathy or haemorrhagic disorders.
Do not use in cases of impaired renal or hepatic function.
Do not use in cases of cardiac insufficiency.
Do not use in pregnant or lactating dogs.
Do not use in animals intended for breeding purposes.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Do not use in cases of known hypersensitivity to sulphonamides.
Do not use in any dehydrated, hypovolemic or hypotensive animal, as there is a
potential risk of increased renal toxicity.
Dogs:
Common
(1 to 10 animals / 100 animals
treated):
Vomiting
(1)
, Diarrhoea
(1)
, Soft stool
(1)
Uncommon
(1 to 10 animals / 1 000
animals treated):
Apathy, Appetite loss
Haemorrhagic diarrhoea, Gastric ulcer
Undetermined frequency
(cannot be
estimated from the available
data)
Elevated blood urea nitrogen (BUN), Elevated
cholesterol (total)
(1)
Most cases recover without treatment.
In case of adverse reactions the use of the veterinary medicinal product should be
stopped and general supportive therapy, as for clinical overdose with NSAIDs, should
be applied until complete resolution of the signs. Particular attention should be paid
to maintain haemodynamic status.
Gastrointestinal protectants and parenteral fluids, as appropriate, may be required for
animals that experience gastrointestinal or renal adverse reactions.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
Do not administer other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or
glucocorticoids concurrently or within 2 weeks of the last administration of this
veterinary medicinal product.

Special precautions for safe use in the target species:
Since the safety of the medicinal product has not been fully demonstrated in very
young animals, careful monitoring is advised during the treatment of young dogs
aged less than 6 months.
The active metabolite of enflicoxib exhibits an extended plasma half-life due to its low
rate of elimination. Use this veterinary medicinal product under strict veterinary
monitoring where there is a risk of gastrointestinal ulceration, or if the animal
previously displayed intolerance to NSAIDs.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
This veterinary medicinal product can cause hypersensitivity (allergic) reactions.
People with known hypersensitivity to NSAIDs should avoid contact with the
veterinary medicinal product.
Some NSAIDs may be harmful for the unborn child, especially during the third
trimester of pregnancy. Pregnant women should administer this veterinary medicinal
product with care.
Ingestion of this veterinary medicinal product may be harmful, especially for children,
and prolonged pharmacological effects leading to e.g. gastrointestinal disorders may
be observed. To avoid accidental ingestion, administer the tablet to the dog
immediately after removal from the blister packaging and do not split or crush tablets.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.
No drug-interaction studies have been performed. In common with other NSAIDs,
this veterinary medicinal product should not be administered simultaneously with
other NSAIDs or glucocorticoids.
Animals should be carefully monitored if this veterinary medicinal product is
administered simultaneously with an anticoagulant.
Enflicoxib is highly bound to plasma proteins and may compete with other highly
bound substances, such that concomitant administration may result in toxic effects.
Pre-treatment with other anti-inflammatory substances may result in additional or
increased adverse reactions. To avoid such adverse reactions when this veterinary
medicinal product is to be administered in replacement to another NSAID, ensure an
appropriate treatment-free period before administering the first dose. The treatment-
free period should, however, consider the pharmacology of the medicinal products
previously used.
Concurrent administration of potentially nephrotoxic veterinary medicinal products
should be avoided.
This veterinary medicinal product does not require any special temperature storage
conditions.
Keep the blisters in the outer carton in order to protect from light.
In order to avoid any accidental ingestion, store tablets out of reach of animals.
Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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