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POM-V Prescription Required

Cronyxin Injection 50 mg/ml Solution for Injection

Active ingredient: Flunixin

Form

Injection

Species

Cattle Horses

Manufacturer

Bimeda Animal Health Limited

VMD MA No.

50146/4011

What it's used for

Cattle respiratory disease. It has also been shown to have some benefit in the treatment of experimental acute bovine pulmonary emphysema (Fog fever). Cron...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Flunixin

  1. 1

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  2. 2

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Prescription required

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Clinical information

Cronyxin Injection 50 mg/ml Solution for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Cattle
respiratory disease. It has also been shown to have some
benefit in the treatment of experimental acute bovine
pulmonary emphysema (Fog fever).
Cronyxin injection may be used as adjunctive therapy in the
treatment of acute mastitis.
Horses
musculoskeletal disorders.
It is also indicated for the alleviation of visceral pain associated with
colic.

Revised: June 2020
AN: 00138/2020
Cattle
bodyweight (equivalent to 2.2 mg flunixin per kg) injected
intravenously and repeated as necessary at 24 hour intervals
for up to 5 consecutive days. The cause of acute
inflammatory conditions should be determined and treated
with concomitant therapy.
Horses
recommended dose is 1 ml Cronyxin Injection per 45 kg
bodyweight (equivalent to 1.1 mg flunixin per kg) injected
intravenously and repeated as necessary at 24 hour intervals
for up to 5 consecutive days according to clinical response.

Revised: June 2020
AN: 00138/2020
For use in equine colic, the recommended dose is 1 ml
Cronyxin Injection per 45 kg bodyweight (equivalent to 1.1 mg
flunixin per kg) injected intravenously and repeated once or
twice if signs of colic recur. The cause of colic should be
determined and treated with concomitant therapy.
Do not exceed the stated dose or duration of treatment.
Use is contra-indicated in animals suffering from cardiac, hepatic or
renal disease, where there is the possibility of gastro-intestinal
ulceration or bleeding, where this is evidence of blood dyscrasia or
hypersensitivity to the product.
Do not administer other NSAIDs concurrently or within 24 hours of
each other.
Avoid intra-arterial injection.
Avoid use in dehydrated, hypovolaemic or hypotensive animals, as
there is a potential risk of increased renal toxicity.
Prolonged use of NSAIDs, including flunixin, may predispose or lead to
gastrointestinal irritation, and in severe cases, ulceration.
NSAIDs can cause inhibition of phagocytosis and hence in the
treatment of inflammatory conditions associated with bacterial
infections, appropriate concurrent antimicrobial therapy should be
instigated.

i. Special precautions for use in animals
Administer by slow intravenous injection.
Do not mix Cronyxin with other medicaments prior to
administration.
Do not administer to racehorses within 8 days of racing.
Some NSAIDs may be highly bound to plasma proteins and
compete with other highly bound drugs to produce an increase
in non-bound pharmacologically active concentrations, which
can lead to toxic effects.
Use in any animal less than 6 weeks of age or in aged animals
may involve additional risk. If such use cannot be avoided
animals may require a reduced dosage and careful clinical
management.
It is preferable that flunixin is not administered to animals
undergoing general anaesthesia until fully recovered.
Concurrent administration of potentially nephrotoxic drugs
should be avoided.

Revised: June 2020
AN: 00138/2020
ii. Special safety precautions to be taken by the person
administering the veterinary product to animals
Avoid eye contact and direct contact with skin.
To avoid possible sensitisation reactions, avoid contact with
skin. Gloves should be worn during application.
Wash hands after use.
In the case of accidental contact with eyes, rinse immediately
with plenty of water and seek medical advice.
The product may cause reactions in sensitive individuals. If you
have known hypersensitivity to non-steroidal anti-inflammatory
products, do not handle the product. Reactions may be serious.
Avoid self-injection.
Following withdrawal of the first dose, use the product within 28 days.
Do not store above 25°C.
Not to be used in horses intended for human consumption.
Treated horses may never be slaughtered for human consumption.
The horse must have been declared as not intended for human
consumption under national horse passport legislation.
Cattle may be slaughtered for human consumption only after 8 days
from the last treatment.
Milk from lactating cows should be discarded during treatment. Milk for
cows should only be taken for human consumption from 12 hours
following cessation of treatment.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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