POM-V Prescription Required

Coccibal 400 mg/ml Solution for Use in Drinking Water for Chickens and Turkeys

Active ingredient: Amprolium

Form

Solution

Species

Chickens Turkeys

Manufacturer

SP Veterinaria, S.A.

VMD MA No.

36967/4009

What it's used for

Treatment of intestinal coccidiosis caused by Eimeria spp.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Amprolium

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Coccibal 400 mg/ml Solution for Use in Drinking Water for Chickens and Turkeys — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Treatment of intestinal coccidiosis caused by Eimeria spp.

Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.

Chickens, turkeys:
None known.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

Revised: May 2024
AN: 03888/2022Page 3 of 6

As with any antimicrobial, frequent and repeated use of antiprotozoal agents of the
same class can lead to resistance development. Cross-resistance has been shown
between amprolium and anticoccidial drugs having the same mode of action. Use of
the veterinary medicinal product/amprolium should be carefully considered when
susceptibility testing has shown resistance to amprolium/anticoccidials because its
effectiveness may be reduced. As with all anticoccidials, prolonged use may result in
the development of resistant strains.

Revised: May 2024
AN: 03888/2022Page 2 of 6
In case of detection of lack of efficacy during treatment, communicate it to competent
national authorities.

Special precautions for use in animals
The veterinary medicinal product is not intended for prophylaxis.
This veterinary medicinal product should be reserved in case of coccidiosis outbreaks
due to non-availability of vaccine, in case of lack of efficacy of vaccine and in
vaccinated flocks if a severe coccidial challenge is diagnosed before immunity has
fully developed.
Use of the veterinary medicinal product should be based on identification and
susceptibility testing of the target pathogen(s). If this is not possible, therapy should
be based on epidemiological information and knowledge of susceptibility of the target
pathogens at farm level, or at local/regional level. Use of the veterinary medicinal
product should be in accordance with official, national and regional antimicrobial
policies.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
This veterinary medicinal product is acidic and may cause irritation to, or corrosion of,
the skin, eyes, throat and airways.
Avoid all physical contact with the product, including any vapours.
Do not eat, drink or smoke whilst handling this product.
Wear impervious gloves and protective glasses when handling the product.
The selected protective gloves should satisfy the specifications of EU Directive
89/686/EEC and the standard EN 374 derived from it.
In the case of contact with skin or eyes, wash the affected area with clean running
water immediately and remove any contaminated clothes. If irritation persists, seek
medical advice and show the label to the physician.
In case of accidental ingestion, rinse the mouth with fresh water, seek medical advice
immediately and show the label to the physician.
People with known hypersensitivity to amprolium or to sorbic acid should avoid
contact with the veterinary medicinal product.
Wash hands and exposed skin after use.
Special precautions for the protection of the environment
Amprolium is classified as a very persistent substance in soil.
Other precautions
Not applicable.

Amprolium is a thiamine analogue. Therefore, the efficacy of amprolium may be
reduced during a simultaneous administration of products containing vitamin B-
complex.

Do not store above 30°C.

Chickens and turkeys:
Meat and offal: zero days
Eggs: zero days
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.