POM-V
Prescription Required
Companion Animal
Clevor 30 mg/ml Eye Drops, Solution in Single-dose Container for Dogs
Active ingredient: Ropinirole
Form
Drops
Species
Dogs
Manufacturer
Orion Corporation
VMD MA No.
06043/5000
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Clinical information
Clevor 30 mg/ml Eye Drops, Solution in Single-dose Container for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
The veterinary medicinal product should always be used under direction of a
veterinarian both at the clinic and, if evaluated to be appropriate by the responsible
veterinarian, at home in an asymptomatic dog having a history of ingesting toxic
substances.
The product is to be administered into the eye, at a dose of 1–8 eye drops. The
volume of one drop is approximately 27 µl. Each eye drop contains 810 µg of
ropinirole. The dose is equivalent to 2–15 µl/kg bw in dogs. The number of eye drops
in each body weight group corresponds to the target dose of 3.75 mg/m
body
surface area (dose range 2.7–5.4 mg/m
). These doses have been tested in dogs
weighing between 1.8 kg and 100 kg (0.15–2.21 m
body surface area).
When a quantity of 2 to 4 drops is to be administered, the dose should be divided
between both eyes. For example, for the administration of 3 drops: administer
2 drops into the right eye and 1 drop into the left eye.
When a quantity of 6 or 8 drops is to be administered, the dose should be divided
into 2 alternate administrations given 1–2 minutes apart. For example, for the
administration of 6 drops: administer 2 drops into the right eye and 2 drops into the
left eye, then after 1–2 minutes pause administer a further 1 drop into each eye.
If the dog does not vomit within 15 minutes after administration of the initial dose a
second dose may be given 15 to 20 minutes after administration of the initial dose.
The second dose should be the same number of drops as the initial dose. It is
recommended to record the time of first administration.
If the dog does not vomit after the second dose, or if it experiences prolonged
vomiting or other side effects, contact the responsible veterinarian for further
instructions.
Be careful not to touch the dropper tip after opening the container in case a second
dose is necessary.
The following dosing table provides the dose in drops to be administered
corresponding to the dog’s bodyweight.
Body weight
(kg)
Body surface
area
(m
)
Number of
eye drops
Ropinirole
(µg)
Ropinirole
(mg/m
body
surface area)
Ropinirole
(µg/kg)
1.8–50.15–0.3018105.4–2.7450–1625.1–100.30–0.4721 6205.4–3.4318–16210.1–200.48–0.7532 4305.1–3.2240–12120.1–350.75–1.0943 2404.3–3.0161–9335.1–601.10–1.5764 8604.4–3.1138–8160.1–1001.57–2.2186 4804.1–2.9108–64.5
Instructions for use
OPENING THE CONTAINER:
Open the container by twisting off the tail.
Be careful not to touch the dropper tip after opening the
container.
ADMINISTRATION:
Keep the dog’s head steady in a slightly upright position. Hold
the container in an upright position without touching the eye.
Rest your little finger on the forehead of the dog to maintain the
distance between the container and the eye. Squeeze the
prescribed number of drops into the eye(s).
STORING THE OPENED CONTAINER:
Do not leave the container unattended during the
administration procedure. After opening place the container
back into the pouch in case a second dose is necessary.
REPEATED DOSE:
In case the dog does not vomit within 15 minutes after the
initial administration, a second dose can be given 15 to
20 minutes after administration of the initial dose. The
additional dose should be the same as the initial dose.
veterinarian both at the clinic and, if evaluated to be appropriate by the responsible
veterinarian, at home in an asymptomatic dog having a history of ingesting toxic
substances.
The product is to be administered into the eye, at a dose of 1–8 eye drops. The
volume of one drop is approximately 27 µl. Each eye drop contains 810 µg of
ropinirole. The dose is equivalent to 2–15 µl/kg bw in dogs. The number of eye drops
in each body weight group corresponds to the target dose of 3.75 mg/m
body
surface area (dose range 2.7–5.4 mg/m
). These doses have been tested in dogs
weighing between 1.8 kg and 100 kg (0.15–2.21 m
body surface area).
When a quantity of 2 to 4 drops is to be administered, the dose should be divided
between both eyes. For example, for the administration of 3 drops: administer
2 drops into the right eye and 1 drop into the left eye.
When a quantity of 6 or 8 drops is to be administered, the dose should be divided
into 2 alternate administrations given 1–2 minutes apart. For example, for the
administration of 6 drops: administer 2 drops into the right eye and 2 drops into the
left eye, then after 1–2 minutes pause administer a further 1 drop into each eye.
If the dog does not vomit within 15 minutes after administration of the initial dose a
second dose may be given 15 to 20 minutes after administration of the initial dose.
The second dose should be the same number of drops as the initial dose. It is
recommended to record the time of first administration.
If the dog does not vomit after the second dose, or if it experiences prolonged
vomiting or other side effects, contact the responsible veterinarian for further
instructions.
Be careful not to touch the dropper tip after opening the container in case a second
dose is necessary.
The following dosing table provides the dose in drops to be administered
corresponding to the dog’s bodyweight.
Body weight
(kg)
Body surface
area
(m
)
Number of
eye drops
Ropinirole
(µg)
Ropinirole
(mg/m
body
surface area)
Ropinirole
(µg/kg)
1.8–50.15–0.3018105.4–2.7450–1625.1–100.30–0.4721 6205.4–3.4318–16210.1–200.48–0.7532 4305.1–3.2240–12120.1–350.75–1.0943 2404.3–3.0161–9335.1–601.10–1.5764 8604.4–3.1138–8160.1–1001.57–2.2186 4804.1–2.9108–64.5
Instructions for use
OPENING THE CONTAINER:
Open the container by twisting off the tail.
Be careful not to touch the dropper tip after opening the
container.
ADMINISTRATION:
Keep the dog’s head steady in a slightly upright position. Hold
the container in an upright position without touching the eye.
Rest your little finger on the forehead of the dog to maintain the
distance between the container and the eye. Squeeze the
prescribed number of drops into the eye(s).
STORING THE OPENED CONTAINER:
Do not leave the container unattended during the
administration procedure. After opening place the container
back into the pouch in case a second dose is necessary.
REPEATED DOSE:
In case the dog does not vomit within 15 minutes after the
initial administration, a second dose can be given 15 to
20 minutes after administration of the initial dose. The
additional dose should be the same as the initial dose.
Do not use in dogs with depression of the central nervous system, seizures or other
marked neurologic impairments that could lead to aspiration pneumonia.
Do not use in dogs which are hypoxic, dyspnoeic or lacking pharyngeal reflexes.
Do not use in cases of the ingestion of sharp foreign objects, corrosive agents (acids
or alkalis), volatile substances or organic solvents.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
marked neurologic impairments that could lead to aspiration pneumonia.
Do not use in dogs which are hypoxic, dyspnoeic or lacking pharyngeal reflexes.
Do not use in cases of the ingestion of sharp foreign objects, corrosive agents (acids
or alkalis), volatile substances or organic solvents.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Dogs:
Very common
(> 1 animal / 10 animals treated):
Increased heart rate
Eye redness
, Ocular discharge
, Third
eyelid protrusion
, Blepharospasm
Lethargy
Common
(1 to 10 animals / 100 animals treated):
Vomiting
, Diarrhoea
Conjunctival oedema
, Eye itching
Ataxia
, Tremors
Tachypnoea
Uncommon
(1 to 10 animals / 1 000 animals
treated):
Corneal ulcer
Transient mild
Transient mild or moderate
Extended vomiting (for more than 60 minutes)
In dogs with extended vomiting and other clinical signs related to the
pharmacological action of the active substance (e.g. eye redness, increased heart
rate or tremors), dopamine antagonists such as metoclopramide or domperidone
may be used to manage these clinical signs.
Maropitant does not reverse the clinical signs related to the pharmacological action of
ropinirole.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
Very common
(> 1 animal / 10 animals treated):
Increased heart rate
Eye redness
, Ocular discharge
, Third
eyelid protrusion
, Blepharospasm
Lethargy
Common
(1 to 10 animals / 100 animals treated):
Vomiting
, Diarrhoea
Conjunctival oedema
, Eye itching
Ataxia
, Tremors
Tachypnoea
Uncommon
(1 to 10 animals / 1 000 animals
treated):
Corneal ulcer
Transient mild
Transient mild or moderate
Extended vomiting (for more than 60 minutes)
In dogs with extended vomiting and other clinical signs related to the
pharmacological action of the active substance (e.g. eye redness, increased heart
rate or tremors), dopamine antagonists such as metoclopramide or domperidone
may be used to manage these clinical signs.
Maropitant does not reverse the clinical signs related to the pharmacological action of
ropinirole.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
Instructions for use
OPENING THE CONTAINER:
Open the container by twisting off the tail.
Be careful not to touch the dropper tip after opening the
container.
ADMINISTRATION:
Keep the dog’s head steady in a slightly upright position. Hold
the container in an upright position without touching the eye.
Rest your little finger on the forehead of the dog to maintain the
distance between the container and the eye. Squeeze the
prescribed number of drops into the eye(s).
STORING THE OPENED CONTAINER:
Do not leave the container unattended during the
administration procedure. After opening place the container
back into the pouch in case a second dose is necessary.
REPEATED DOSE:
In case the dog does not vomit within 15 minutes after the
initial administration, a second dose can be given 15 to
20 minutes after administration of the initial dose. The
additional dose should be the same as the initial dose.
3.10 Symptoms of overdose (and where applicable, emergency procedures and
antidotes)
The tolerance of this veterinary medicinal product was investigated in a target animal
safety study at all dose levels up to 5 times the clinical dose (that is, up to
12
OPENING THE CONTAINER:
Open the container by twisting off the tail.
Be careful not to touch the dropper tip after opening the
container.
ADMINISTRATION:
Keep the dog’s head steady in a slightly upright position. Hold
the container in an upright position without touching the eye.
Rest your little finger on the forehead of the dog to maintain the
distance between the container and the eye. Squeeze the
prescribed number of drops into the eye(s).
STORING THE OPENED CONTAINER:
Do not leave the container unattended during the
administration procedure. After opening place the container
back into the pouch in case a second dose is necessary.
REPEATED DOSE:
In case the dog does not vomit within 15 minutes after the
initial administration, a second dose can be given 15 to
20 minutes after administration of the initial dose. The
additional dose should be the same as the initial dose.
3.10 Symptoms of overdose (and where applicable, emergency procedures and
antidotes)
The tolerance of this veterinary medicinal product was investigated in a target animal
safety study at all dose levels up to 5 times the clinical dose (that is, up to
12
Dopamine antagonists (such as metoclopramide), neuroleptics (e.g., chlorpromazine,
acepromazine) and other medicinal products with antiemetic properties (e.g.,
maropitant or antihistamines) may reduce the effectiveness of this veterinary
medicinal product.
acepromazine) and other medicinal products with antiemetic properties (e.g.,
maropitant or antihistamines) may reduce the effectiveness of this veterinary
medicinal product.
This veterinary medicinal product does not require any special temperature storage
conditions.
Store the container in the pouch in order to protect from light.
After opening the pouch, the container should be kept in the pouch to protect from
light.
Discard any opened individual pouch or container with any remaining liquid after
30 minutes.
conditions.
Store the container in the pouch in order to protect from light.
After opening the pouch, the container should be kept in the pouch to protect from
light.
Discard any opened individual pouch or container with any remaining liquid after
30 minutes.
). These doses have been tested in dogs
weighing between 1.8 kg and 100 kg (0.15–2.21 m
body surface area).
When a quantity of 2 to 4 drops is to be administered, the dose should be divided
between both eyes. For example, for the administration of 3 drops: administer
2 drops into the right eye and 1 drop into the left eye.
When a quantity of 6 or 8 drops is to be administered, the dose should be divided
into 2 alternate administrations given 1–2 minutes apart. For example, for the
administration of 6 drops: administer 2 drops into the right eye and 2 drops into the
left eye, then after 1–2 minutes pause administer a further 1 drop into each eye.
If the dog does not vomit within 15 minutes after administration of the initial dose a
second dose may be given 15 to 20 minutes after administration of the initial dose.
The second dose should be the same number of drops as the initial dose. It is
recommended to record the time of first administration.
If the dog does not vomit after the second dose, or if it experiences prolonged
vomiting or other side effects, contact the responsible veterinarian for further
instructions.
Be careful not to touch the dropper tip after opening the container in case a second
dose is necessary.
The following dosing table provides the dose in drops to be administered
corresponding to the dog’s bodyweight.
Body weight
(kg)
Body surface
area
(m
)
Number of
eye drops
Ropinirole
(µg)
Ropinirole
(mg/m
body
surface area)
Ropinirole
(µg/kg)
1.8–50.15–0.3018105.4–2.7450–1625.1–100.30–0.4721 6205.4–3.4318–16210.1–200.48–0.7532 4305.1–3.2240–12120.1–350.75–1.0943 2404.3–3.0161–9335.1–601.10–1.5764 8604.4–3.1138–8160.1–1001.57–2.2186 4804.1–2.9108–64.5
Instructions for use
OPENING THE CONTAINER:
Open the container by twisting off the tail.
Be careful not to touch the dropper tip after opening the
container.
ADMINISTRATION:
Keep the dog’s head steady in a slightly upright position. Hold
the container in an upright position without touching the eye.
Rest your little finger on the forehead of the dog to maintain the
distance between the container and the eye. Squeeze the
prescribed number of drops into the eye(s).
STORING THE OPENED CONTAINER:
Do not leave the container unattended during the
administration procedure. After opening place the container
back into the pouch in case a second dose is necessary.
REPEATED DOSE:
In case the dog does not vomit within 15 minutes after the
initial administration, a second dose can be given 15 to
20 minutes after administration of the initial dose. The
additional dose should be the same as the initial dose.
3.10 Symptoms of overdose (and where applicable, emergency procedures and
antidotes)
The tolerance of this veterinary medicinal product was investigated in a target animal
safety study at all dose levels up to 5 times the clinical dose (that is, up to
124.6 µl/kg) when given on two occasions, 15–20 minutes apart, every day for
3 days. The clinical signs (lethargy, tachycardia, tremors, ataxia, uncoordinated
movement, hyperaemia of the eye, ocular discharge, protrusion of the 3
rd
eyelid and
blepharospasm) were comparable in frequency and severity between the different
dose groups. Increased mean heart rate was observed one hour after treatment with
all three doses (1X, 3X, 5X) and went back to normal levels after 6 hours.
3.11 Special restrictions for use and special conditions for use, including
restrictions on the use of antimicrobial and antiparasitic veterinary
medicinal products in order to limit the risk of development of resistance
Not applicable.
3.12 Withdrawal periods
Not applicable.
4.
weighing between 1.8 kg and 100 kg (0.15–2.21 m
body surface area).
When a quantity of 2 to 4 drops is to be administered, the dose should be divided
between both eyes. For example, for the administration of 3 drops: administer
2 drops into the right eye and 1 drop into the left eye.
When a quantity of 6 or 8 drops is to be administered, the dose should be divided
into 2 alternate administrations given 1–2 minutes apart. For example, for the
administration of 6 drops: administer 2 drops into the right eye and 2 drops into the
left eye, then after 1–2 minutes pause administer a further 1 drop into each eye.
If the dog does not vomit within 15 minutes after administration of the initial dose a
second dose may be given 15 to 20 minutes after administration of the initial dose.
The second dose should be the same number of drops as the initial dose. It is
recommended to record the time of first administration.
If the dog does not vomit after the second dose, or if it experiences prolonged
vomiting or other side effects, contact the responsible veterinarian for further
instructions.
Be careful not to touch the dropper tip after opening the container in case a second
dose is necessary.
The following dosing table provides the dose in drops to be administered
corresponding to the dog’s bodyweight.
Body weight
(kg)
Body surface
area
(m
)
Number of
eye drops
Ropinirole
(µg)
Ropinirole
(mg/m
body
surface area)
Ropinirole
(µg/kg)
1.8–50.15–0.3018105.4–2.7450–1625.1–100.30–0.4721 6205.4–3.4318–16210.1–200.48–0.7532 4305.1–3.2240–12120.1–350.75–1.0943 2404.3–3.0161–9335.1–601.10–1.5764 8604.4–3.1138–8160.1–1001.57–2.2186 4804.1–2.9108–64.5
Instructions for use
OPENING THE CONTAINER:
Open the container by twisting off the tail.
Be careful not to touch the dropper tip after opening the
container.
ADMINISTRATION:
Keep the dog’s head steady in a slightly upright position. Hold
the container in an upright position without touching the eye.
Rest your little finger on the forehead of the dog to maintain the
distance between the container and the eye. Squeeze the
prescribed number of drops into the eye(s).
STORING THE OPENED CONTAINER:
Do not leave the container unattended during the
administration procedure. After opening place the container
back into the pouch in case a second dose is necessary.
REPEATED DOSE:
In case the dog does not vomit within 15 minutes after the
initial administration, a second dose can be given 15 to
20 minutes after administration of the initial dose. The
additional dose should be the same as the initial dose.
3.10 Symptoms of overdose (and where applicable, emergency procedures and
antidotes)
The tolerance of this veterinary medicinal product was investigated in a target animal
safety study at all dose levels up to 5 times the clinical dose (that is, up to
124.6 µl/kg) when given on two occasions, 15–20 minutes apart, every day for
3 days. The clinical signs (lethargy, tachycardia, tremors, ataxia, uncoordinated
movement, hyperaemia of the eye, ocular discharge, protrusion of the 3
rd
eyelid and
blepharospasm) were comparable in frequency and severity between the different
dose groups. Increased mean heart rate was observed one hour after treatment with
all three doses (1X, 3X, 5X) and went back to normal levels after 6 hours.
3.11 Special restrictions for use and special conditions for use, including
restrictions on the use of antimicrobial and antiparasitic veterinary
medicinal products in order to limit the risk of development of resistance
Not applicable.
3.12 Withdrawal periods
Not applicable.
4.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Related Conditions
Same active ingredient
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