POM-V Prescription Required

Cevazuril 50 mg/ml, Oral Suspension for Piglets and Calves

Active ingredient: Toltrazuril

Form

Liquid

Species

Cattle Pigs

Manufacturer

Ceva Sante Animale

VMD MA No.

14966/5031

What it's used for

Revised October 2025 Calves: For the prevention of clinical signs of cystoisosporosis and reduction of coccidia shedding in housed calves replacing cows pr...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Toltrazuril

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Cevazuril 50 mg/ml, Oral Suspension for Piglets and Calves — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Revised October 2025
Calves:
For the prevention of clinical signs of cystoisosporosis and reduction of coccidia
shedding in housed calves replacing cows producing milk for human consumption
(dairy cows) on farms with a confirmed history of cystoisosporosis, caused by
Eimeria bovis or Eimeria zuernii

Shake well before use.
Piglets:
Individual animal treatment.
Each piglet to be treated on day 3-5 of life with a single oral dose of 20 mg
toltrazuril/kg body weight corresponding to 0.4 ml oral suspension per kg body
weight.
Treatment during an outbreak will be of limited value for the individual piglet
because of damage to the small intestine having already occurred.
Due to the small volumes required to treat individual piglets, use of dosing
equipment with a dose accuracy of 0.1 ml is recommended.
Calves:
Each calf should be treated with a single oral dose of 15 mg toltrazuril/kg body weight
corresponding to 3 ml oral suspension per 10 kg body weight.
If animals are to be treated collectively, reasonably homogeneous groups should
be set up, and all animals of a group should be dosed at the rate corresponding to
the heaviest one.
To ensure administration of a correct dose, body weight should be determined as
accurately as possible.

Do not use in cases of known hypersensitivity to the active substance or to any of
the excipients.
Cattle (for environmental reasons):
Do not use in calves weighing more than 80 kg bodyweight.
Do not use in fattening units such as veal or beef calves.
For more details, see section 3.5, precautions for the protection of the environment.

Cattle, pigs: None known.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

As with any antiparasiticide, frequent and repeated use of antiprotozoals from the
same class may lead to the development of resistance.
It is recommended to treat all piglets in a litter and all calves in a pen.
Hygienic measures may reduce the risk of porcine and bovine cystoisosporosis. It is
therefore, recommended to concomitantly improve the hygiene conditions in the
concerned facility, particularly by increasing dryness and cleanliness.
To alter the course of an established clinical coccidial infection in individual animals
already showing signs of diarrhoea, additional supportive therapy may be required.
To obtain maximum benefit, animals should be treated before the expected onset of
clinical signs, i.e. in the prepatent period.

Special precautions for safe use in the target species:
None known.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Wash any splashes from skin or eyes immediately with
water.
Wash hands after product administration.
People with known hypersensitivity to any of the ingredients should avoid contact
with the veterinary medicinal product.
Special precautions for the protection of the environment:
The major metabolite of toltrazuril, toltrazuril sulfone (ponazuril), has been shown to
be both persistent (half-life > 1 year) and mobile in soil and to be toxic to plants.
In order to prevent any adverse effects on plants and possible contamination of
groundwater, manure from treated calves must not be spread onto land without
dilution with manure from toltrazuril untreated cattle. Manure from treated calves
must be diluted with at least 3 times the weight of manure from toltrazuril untreated
cattle before it can be spread onto land.

Revised October 2025

None known.
There is no interaction in combination with iron supplementation.

This veterinary medicinal product does not require any special storage conditions.

Meat and offal:
Pigs (piglets): 77 days.
Cattle (calves): 63 days.
Not authorised for use in animals producing milk for human consumption.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.