Carprodyl F 20 mg Tablets for Dogs

Special precautions for use in animals
Use in aged dogs may involve additional risk. If such a use cannot be avoided, dogs may
require careful clinical management.
Avoid use in any dehydrated, hypoproteinemic, hypovolaemic or hypotensive dog, as there
is a potential risk of increased renal toxicity.
NSAIDs can cause inhibition of phagocytosis and hence in the treatment of inflammatory
conditions associated with bacterial infection, appropriate concurrent antimicrobial therapy
should be instigated.
Response to long term treatment should be monitored at regular intervals by a veterinary
surgeon.
As the tablets are flavoured, they should be stored in a safe place out of the reach of
animals.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
In the event of accidental ingestion of the tablets, seek medical advice and show the
doctor the package leaflet.
Wash hands after handling the product.
4.6 Adverse reactions (frequency and seriousness)
Typical undesirable effects associated with NSAIDs, such as vomiting, soft
faeces/diarrhea, faecal occult blood, loss of appetite and lethargy have been reported.
These adverse reactions occur generally within the first treatment week and are in most
cases transient and disappear following termination of the treatment but in very rare cases
may be serious or fatal.
Rare cases of gastrointestinal bleeding are reported.
If adverse reactions occur, use of the product should be stopped and the advice of a
veterinarian should be sought.
As with other NSAIDs there is a rare risk of renal or idiosyncratic hepatic adverse events.
4.7 Use during pregnancy, lactation or lay
Studies in laboratory species (rat and rabbit) have shown evidence of foetotoxic effects of
carprofen at doses close to the therapeutic dose.
In dogs, the safety of the veterinary medicinal product has not been investigated during
pregnancy and lactation. Do not use in pregnant or lactating bitches.
4.8 Interaction with other medicinal products and other forms of interaction
Carprofen must not be administered with glucocorticoids.
Do not administer other NSAIDs concurrently or within 24 hours of each other. Some
NSAIDs may be highly bound to plasma proteins and compete with other highly bound
drugs, which can lead to toxic effects.

Revised: October 2025
AN: 01757/2025Page 3 of 5
Concurrent administration of potential nephrotoxic drugs should be avoided.
4.9 Amounts to be administered and administration route
For oral administration.
4 mg carprofen per kg bodyweight per day
To limit the inflammation and relieve the pain caused by musculo-skeletal disorders and
degenerative joint disease:
An initial dose of 4 mg carprofen per kg bodyweight per day given as a single daily dose or
in two equally divided doses. The daily dose may be reduced, subject to clinical response.
Duration of treatment will be dependent upon the response seen. Long term treatment
should be under regular veterinary supervision.
To extend analgesic and anti-inflammatory cover post-operatively, parenteral preoperative
treatment with carprofen injection may be followed with carprofen tablets at 4mg/kg/day for
5 days.
Do not exceed the stated dose.
The tablets are flavoured and consequently taken by most of dogs voluntarily.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
No signs of toxicity appeared when dogs were treated with carprofen at levels up to 6
mg/kg twice daily for 7 days (3 times the recommended dose rate of 4 mg/kg) and 6 mg/kg
once daily for a further 7 days (1.5 times the recommended dose rate of 4 mg/kg).
There is no specific antidote for carprofen overdosage but general supportive therapy, as
applied to clinical overdosage with NSAIDs, should be applied.
Severe adverse reactions may occur if large quantities are ingested. If you suspect that
your dog has consumed tablets above the labelled dose, contact your veterinarian.
4.11 Withdrawal period(s)
Not applicable.
5.