Cardisure Flavoured 5 mg Tablets for Dogs
Active ingredient: Pimobendan
Form
Tablet
Species
Manufacturer
Eurovet Animal Health B.V.
VMD MA No.
16849/5018
What it's used for
For the treatment of dilated cardiomyopathy in the preclinical stage (asymptomatic with an increase in left ventricular end-systolic and end-diastolic diam...
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Paying less for Pimobendan
-
1
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2
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Cardisure Flavoured 5 mg Tablets for Dogs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
with an increase in left ventricular end-systolic and end-diastolic diameter) in
Doberman Pinschers following echocardiographic diagnosis of cardiac disease.
To ensure a correct dosage, body weight should be determined as accurately
as possible.
The tablets should be administered orally at a dose range of 0.2 mg to 0.6 mg
pimobendan/kg body weight per day. The preferable daily dose is 0.5 mg
pimobendan/kg body weight. The dose should be divided into two
administrations (0.25 mg/kg body weight each), one half of the dose in the
morning and the other half approximately 12 hours later. The maintenance
dose should be individually adjusted by the responsible veterinarian according
to the severity of the disease.
AN: 03577/2024 & 03578/2024
The veterinary medicinal product may be combined with a diuretic treatment, e.g.
furosemide.
To break a double scored tablet into quarters, place the
tablet on an even surface with the scored side up and
apply pressure on the middle with your thumb.
Each dose should be given approximately one hour
before feeding.
where an augmentation of cardiac output is not possible for functional or
anatomical reasons (e.g. aortic stenosis).
See also section 3.7.
Rare
(1 to 10 animals / 10 000 animals
treated):
Increased heart rate
a,b
, Increase in mitral
valve regurgitation
c
Vomiting
b
, Diarrhoea
d
Anorexia
d
, Lethargy
d
Very rare
(<1 animal / 10 000 animals
treated, including isolated
reports):
Mucosa petechiae
e
, Subcutaneous
haemorrhage
e
a
Moderate positive chronotropic effect.
b
These effects are dose-dependent and may be avoided by reducing the dose
in these cases.
AN: 03577/2024 & 03578/2024
c
Has been observed during chronic pimobendan treatment in dogs with mitral
valve disease.
d
Transient.
e
Although a relationship with pimobendan has not been clearly established,
signs of effects on primary haemostasis may be observed during treatment.
These signs disappear when the treatment is withdrawn.
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or its local
representative or the national competent authority via the national reporting
system. See the package leaflet for respective contact details.
least one hour before meals, as absorption is reduced when given with feed.
AN: 03577/2024 & 03578/2024
Special precautions for safe use in the target species:
The veterinary medicinal product is flavoured. To avoid accidental ingestion the
tablets should be stored out of reach of dogs.
An in vitro study in rat tissue demonstrated that pimobendan increased
glucose-induced insulin release from pancreatic in a dose-dependent
manner. If the veterinary medicinal product is administered to diabetic dogs,
blood glucose levels should be carefully monitored.
As pimobendan is metabolised in the liver, particular care should be taken
when administering the veterinary medicinal product to dogs with severe hepatic
insufficiency.
Monitoring of cardiac function and morphology is recommended in animals
treated with pimobendan.(See also section 3.6).
Special precautions to be taken by the person administering the veterinary
medicinal product to animals:
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
Wash hands after use.
To the physician: Accidental ingestion, especially by a child, may lead to the
occurrence of tachycardia, orthostatic hypotension, flushing of the face and
headaches.
Special precautions for the protection of the environment:
Not applicable.
In pharmacological studies no interaction between the cardiac glycoside ouabain
and pimobendan was detected. The pimobendan-induced increase in
contractility of the heart is attenuated in the presence of the calcium antagonist
verapamil and the β-antagonist propranolol.
Return any divided tablet to the opened blister and use within 3 days.
4.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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