Anarthron 100 mg/mL Solution for Injection for Dogs

Dog
Very rare
(<1 animal / 10 000 animals
treated, including isolated
reports)
Emesis
1,2
, diarrhoea
1,2
Lethargy
1,2
, anorexia
1,2
Hypersensitivity reaction
Prolonged activated partial thrombin time
(APTT)
, prolonged thrombin time (TT)
Injection site reaction, injection site swelling
Undetermined frequency
(cannot be estimated from
the available data):
Bleeding disorder (e.g. nasal bleeding,
haemorrhagic diarrhoea, haematoma)
Due to a hypersensitivity reaction.
May require appropriate symptomatic treatment, including antihistamine
administration.
May persist for up to 24 hours after administration in healthy dogs. This very
rarely results in clinical effects, but because of the fibrinolytic action of
pentosan polysulfate sodium, the possibility of internal bleeding from a tumour
or vascular abnormality should be considered if signs develop. It is
recommended that the animal should be monitored for signs of blood loss and
treated appropriately.
Transient.
Reporting adverse events is important. It allows continuous safety monitoring
of a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or the national
competent authority via the national reporting system. See the package leaflet
for respective contact details.