Synulox
The UK's Most Prescribed Vet Antibiotic
Amoxicillin/clavulanic acid for bacterial infections. Available as palatable tablets and drops. Save up to 50% buying online with a prescription.
Buy Synulox at UK pharmacy prices
UK registered pharmacies dispense the same Synulox your vet prescribes, often for less. Ask your vet for a written prescription (capped at £21 under the CMA Order, from 2027), then fill it online.
Affiliate link to The Pharm Pet Co., a UK registered veterinary pharmacy. We may earn a small commission, at no extra cost to you. Always follow your vet's guidance on medication choice and dosing.
What is Synulox?
Synulox is a veterinary antibiotic manufactured by Zoetis containing amoxicillin trihydrate and clavulanic acid. This combination is extremely effective because clavulanic acid inhibits beta-lactamase enzymes that some bacteria produce to resist amoxicillin, making it effective against a wider range of bacterial infections.
It is the veterinary equivalent of Augmentin (the human version) and is one of the most commonly prescribed antibiotics in UK veterinary practice. Available as palatable tablets (50 mg, 250 mg and 500 mg), Synulox Palatable Drops (oral suspension for small dogs and cats), and Synulox RTU injectable.
Synulox treats infections of the skin, soft tissues, urinary tract, respiratory tract and dental/oral cavity. It is bactericidal (kills bacteria) rather than bacteriostatic, and is effective against most common veterinary pathogens including Staphylococci, Streptococci, E. coli and Pasteurella species.
What Does Synulox Treat?
Skin Infections
Pyoderma, wound infections, abscesses, hot spots and infected bites. Skin infections are the most common reason for prescribing Synulox.
Urinary Tract Infections
Cystitis, bladder infections and kidney infections. Very effective against E. coli, the most common urinary pathogen.
Respiratory Infections
Upper and lower respiratory tract infections including kennel cough complications, bronchitis and pneumonia.
Dental Infections
Tooth root abscesses, gum infections and post-dental surgery infections. Often prescribed before and after dental procedures.
Synulox Dosage
Standard dose: 12.5 mg/kg twice daily. Course length varies by condition.
Course length: Skin infections: 5-7 days minimum (deep pyoderma: 3-6 weeks). UTI: 10-14 days. Dental: 5-10 days. Always complete the full course even if symptoms improve.
Side Effects & Warnings
Common Side Effects
- • Mild vomiting or nausea
- • Diarrhoea or soft stools
- • Reduced appetite
- • Mild lethargy
Rare Side Effects
- • Allergic reaction (facial swelling, hives)
- • Severe diarrhoea
- • Yeast overgrowth (secondary)
- • Anaphylaxis (extremely rare)
Synulox Price Comparison
Synulox 50 mg Palatable — 100 tablets
Synulox 250 mg Palatable — 100 tablets
Synulox 500 mg Palatable — 100 tablets
Synulox Palatable Drops 40ml (cats/small dogs)
Alternatives to Synulox
Clavaseptin (Generic Amoxicillin/Clavulanate)
Contains the same active ingredients at a lower price. Manufactured by Vetoquinol. Typically 15-30% cheaper than branded Synulox. Ask your vet to prescribe the generic.
Noroclav (Generic)
Another generic amoxicillin/clavulanate by Norbrook. Same ingredients, same efficacy, typically cheaper. Available in the same tablet sizes.
Convenia Injection (Cefovecin)
Single injection lasting 14 days. Given at the vet, no tablets to give. More expensive (£40-£80 per injection) but useful for cats or dogs that refuse tablets. Different antibiotic class.
Frequently Asked Questions
Synulox treats bacterial infections of the skin, urinary tract, respiratory tract, dental/oral cavity and soft tissues in dogs and cats.
£0.50-£1.50 per tablet at the vet, £0.25-£0.80 online. A 7-day course costs £15-£40 at the vet vs £8-£22 online.
Generally very well tolerated. Mild GI upset (vomiting, diarrhoea) is the most common. Allergic reactions are rare. Always complete the full course.
Same active ingredients but Synulox is veterinary-licensed. Different tablet sizes and formulations. Pharmacologically equivalent.
No. All antibiotics are POM-V in the UK. Your vet must examine your pet first. Prescription fee proposed cap of £21.
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