NexGard Spectra is one of the most prescribed flea, tick, and worming treatments for dogs in the UK. It is a monthly chewable tablet containing afoxolaner (kills fleas and ticks) and milbemycin oxime (treats and prevents roundworm, hookworm, and heartworm). As a POM-V medicine, it requires a veterinary prescription.

Price Comparison

Prices for a 3-pack of NexGard Spectra (medium dog, 7.5–15kg) across UK sources:

  • Direct from your vet: £45–£65
  • Online pharmacies (with prescription): £25–£38
  • Prescription fee: £10–£25 (needed once every 6 months)

Even factoring in the prescription fee, buying from an online pharmacy can save £15–£30 per 3-pack, or £30–£60 per year.

Price by Weight Band

NexGard Spectra comes in 5 weight bands. Larger dogs require more active ingredient and the cost increases accordingly:

  • XS (2–3.5kg): £22–£35 for 3 tablets
  • S (3.5–7.5kg): £24–£38 for 3 tablets
  • M (7.5–15kg): £25–£40 for 3 tablets
  • L (15–30kg): £28–£45 for 3 tablets
  • XL (30–60kg): £32–£50 for 3 tablets

How to Get the Best Price

  1. Ask your vet for a written prescription (they are legally required to provide one)
  2. Compare prices across online pharmacies using VetCost's medication price comparison
  3. Buy in 6-packs rather than 3-packs for a per-unit discount
  4. Set up auto-delivery with some pharmacies for additional savings

Cheaper Alternatives

If NexGard Spectra is too expensive, discuss alternatives with your vet:

  • Simparica Trio: Similar combination product, sometimes slightly cheaper
  • Separate flea/tick + wormer: Using Frontline Plus (NFA-VPS, no prescription needed) for fleas/ticks and Drontal for worms can work out cheaper, though you lose the lungworm and heartworm coverage
  • Bravecto: One chew lasts 12 weeks instead of monthly, which can work out cheaper per month

Is NexGard Spectra Safe?

NexGard Spectra is widely used and generally well tolerated. Common side effects are mild and include temporary vomiting or diarrhoea. It should not be used in dogs with epilepsy or a history of seizures. Always discuss suitability with your vet, especially for breeds with the MDR1 gene mutation (Collies, Shelties, Australian Shepherds).

Last updated: March 2026. Sources: VetCost pharmacy price data, VMD product datasheet.