Isaderm is a topical gel containing fusidic acid (an antibiotic) and betamethasone valerate (a corticosteroid), manufactured by Dechra. It is one of the most commonly prescribed treatments for localised skin infections in dogs, particularly in skin folds, between toes, and around the chin.
Price Comparison
Isaderm gel (15g tube):
- From your vet: £10–£18
- Online pharmacies (with prescription): £6–£12
- Prescription fee: £10–£25
A single tube often lasts several weeks for localised infections. The saving per tube is modest, but for dogs with chronic skin issues needing repeat prescriptions, online purchasing saves 35–50% over time.
What Does Isaderm Treat?
- Localised bacterial skin infections (pyoderma)
- Skin fold dermatitis (common in Bulldogs, Pugs, Shar Peis)
- Interdigital cysts and infections (between toes)
- Chin acne in dogs
- Hot spots (acute moist dermatitis) — as part of treatment
Species and Forms
- Dogs: Topical gel applied thinly to affected areas twice daily for 7–14 days
- Cats: Not licensed for cats, though occasionally used off-label under veterinary direction
Side Effects
- Generally well tolerated when used as directed
- Skin thinning if used long-term (due to the steroid component)
- Antibiotic resistance can develop with overuse or incomplete courses
- Should not be used on large areas of broken skin
- Avoid prolonged use beyond 14 days without veterinary review
Prescription Requirements
Isaderm is POM-V. A veterinary prescription is required, but you can then purchase from online pharmacies.
How to Save
- Written prescription: Save 35–50% by buying from online pharmacies
- Prevention: Regular skin fold cleaning in prone breeds reduces the frequency of infections needing treatment
- Complete the course: Finishing the full course prevents recurrence and the need for repeat purchases
- Compare prices: Use VetCost to compare pharmacy prices
Last updated: March 2026. Sources: VMD product datasheet, CMA provisional decision (October 2025), VetCost pharmacy data.